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Psychiatric Pharmacology > Antidepressants > Flashcards

Antidepressants Flashcards

1
Q

Fluoxetine

A

SSRI

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2
Q

Sertraline

A

SSRI

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3
Q

Paroxetine

A

SSRI

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4
Q

Citalopram

A

SSRI

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5
Q

Fluvoxamine

A

SSRI

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6
Q

Venflaxamine

A

SNRI

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7
Q

Duloxetine

A

SNRI

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8
Q

Mirtazapine

A

Noradrenergic and specific serotonergic antidepressant

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9
Q

Trazodone

A

SARI

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10
Q

Amitriptyline

A

TCA

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11
Q

Lofepramine

A

TCA

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12
Q

Clomipramine

A

TCA

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13
Q

Imipramine

A

TCA

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14
Q

Phenelzine

A

MAOI (Less commonly used)

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15
Q

Tranylcypromine

A

MAOI (Less commonly used)

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16
Q

Isocarboxazid

A

MAOI (Less commonly used)

17
Q

Moclobemide

A

RIMA (Less commonly used)

18
Q

Bupropion

A

Noradrenaline and Dopamine Reuptake Inhibitor (Less commonly used)

19
Q

Pramipexole

A

Dopamine Agonist (Less commonly used)

20
Q

Ropinirole

A

Dopamine Agonist (Less commonly used)

21
Q

Reboxetine

A

Selective Noradrenaline Reuptake Inhibitor (Less commonly used)

22
Q

Agomelatine

A

Melatonin agonist and serotonin antagonist (Less commonly used)

23
Q

Vortioxetine

A

Serotonin modulator (Less commonly used)

24
Q

Indications for SSRIs

A

Depression
Anxiety Disorders
Obsessive-Compulsive Disorder

25
Q

Indications for Mirtazapine

A

Depression (if sedation/ reduced oral intake desirable)

26
Q

Indications for TCAs

A

Depression
Anxiety
Obsessive-Compulsive Disorder (Clomipramine)
Other: nocturnal enuresis, neuropathic pain, narcolepsy

27
Q

Indications for MAOI

A

Depression (atypical; overeating, hypersomnia, anxiety)
Anxiety Disorders
Other: Parkinson Disease, migraine prophylaxis, tuberculosis

28
Q

Side-Effects of SSRIs

A

GI Disturbance (Early)
Anxiety and Agitation (Early)
Loss of Appetite and Weight Loss (Sometimes Weight gain)
Insomnia
Sweating
Sexual Dysfunction

29
Q

Contra-indications for SSRIs

A

Mania
Poorly-controlled Epilepsy
Prolonged QTc interval (citalopram and escitalopram)

30
Q

Side-effects of Mirtazapine

A

Dry Mouth
Headache
Dizziness
Postural hypotension
Tremor
Peripheral Oedema

31
Q

Contra-indications for Mirtazapine

32
Q

Side-Effects of TCAs

A

Anticholinergic (Dry Mouth, Constipation, Urinary Retention, Blurred Vision)
Adrenergic Receptor Blockade (Postural Hypotension)
Histaminergic Receptor Blockade (Weight Gain)
Cardiotoxic Effects

33
Q

Contra-indications for TCAs

A

Recent MI
Cardiac Arrythmias
Acute Porphyria
Heart Block
Risk of overdose

Psychiatric Pharmacology (2 decks)

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