Antidepressant Drugs Flashcards
A patient who has received some traumatic news is panicking and asks for some medication to help settle down. The nurse anticipates giving which drug that is most appropriate for this situation?
a. Diazepam
b. Zolpidem
c. Phenobarbital
d. Cyclobenzaprine
ANS: A
Benzodiazepines such as diazepam are used as anxiolytics, or sedatives. Zolpidem is used as a hypnotic for sleep. Phenobarbital is not used as an anxiolytic but is used for seizure control. Cyclobenzaprine is a muscle relaxant and is not used to reduce anxiety.
A patient has been taking phenobarbital for 2 weeks as part of his therapy for epilepsy. He tells the nurse that he feels tense and that ―the least little thing‖ bothers him now. Which is the correct explanation for this problem?
a. These are adverse effects that usually subside after a few weeks.
b. The drug must be stopped immediately because of possible adverse effects.
c. This drug causes the rapid eye movement (REM) sleep period to increase, resulting in nightmares and restlessness.
d. This drug causes deprivation of REM sleep and may cause the inability to deal with normal stress.
ANS: D
Barbiturates such as phenobarbital deprive people of REM sleep, which can result in agitation. Rebound phenomenon occurs when the drug is stopped (not during therapy), and the proportion of REM sleep increases, sometimes resulting in nightmares. The other options are incorrect.
A man who has been taking phenobarbital for 1 week is found very lethargic and unable to walk after eating out for dinner. His wife states that he has no other prescriptions and that he did not take an overdose—the correct number of pills is in the bottle. The nurse suspects that which of these may have happened?
a. He took a multivitamin.
b. He drank a glass of wine.
c. He took a dose of aspirin.
d. He developed an allergy to the drug.
ANS: B
Alcohol has an additive effect when combined with barbiturates and causes central nervous system (CNS) depression. Multivitamins and aspirin do not interact with barbiturates, and this situation does not illustrate an allergic reaction.
A patient has been taking suvorexant for intermittent insomnia. She calls the nurse to say that when she takes it, she sleeps well, but the next day she feels ―so tired.‖ Which explanation by the nurse is correct?
a. ―Long-term use of this drug results in a sedative effect.‖
b. ―If you take the drug every night, this hangover effect will be reduced.‖
c. ―These drugs affect the sleep cycle, resulting in daytime sleepiness.‖
d. ―These drugs increase the activity of the central nervous system, making you tired the next day.‖
ANS: C
Use of suvorexant result in daytime sleepiness. The other statements are incorrect.
A patient is taking flurazepam three to four nights a week for sleeplessness. She is concerned that she cannot get to sleep without taking the medication. What nonpharmacologic measures should the nurse suggest to promote sleep for this patient?
a. Providing a quiet environment
b. Exercising before bedtime to become tired
c. Consuming heavy meals in the evening to promote sleepiness
d. Drinking hot tea or coffee just before bedtime
ANS: A
Nonpharmacologic approaches to induce sleep include providing a quiet environment, avoiding heavy exercise before bedtime, avoiding heavy meals late in the evening, and drinking warm decaffeinated drinks, such as warm milk, before bedtime.
A patient is brought to the emergency department for treatment of a suspected overdose. The patient was found with an empty prescription bottle of a barbiturate by his bedside. He is lethargic and barely breathing. The nurse would expect which immediate intervention?
a. Starting an intravenous infusion of diluted bicarbonate solution
b. Administering medications to increase blood pressure
c. Implementing measures to maintain the airway and support respirations
d. Administrating naloxone (Narcan) as an antagonist
ANS: C
There are no antagonists/antidotes for barbiturates. Treatment supports respirations and maintains the airway. The other interventions are not appropriate.
Ramelteon is prescribed for a patient with insomnia. The nurse checks the patient‘s medical history, knowing that this medication is contraindicated in which disorder?
a. Coronary artery disease
b. Renal insufficiency
c. Liver disease
d. Anemia
ANS: C
Ramelteon is contraindicated in cases of severe liver dysfunction. The other conditions are not contraindications.
The nurse notes in the patient‘s medication history that the patient is taking cyclobenzaprine. Based on this finding, the nurse interprets that the patient has which disorder?
a. A musculoskeletal injury
b. Insomnia
c. Epilepsy
d. Agitation
ANS: A
Cyclobenzaprine is the muscle relaxant most commonly used to reduce spasms following musculoskeletal injuries. It is not appropriate for insomnia, epilepsy, or agitation.
A patient has experienced insomnia for months, and the physician has prescribed a medication to help with this problem. The nurse expects which drug to be used for long-term treatment of insomnia?
a. Secobarbital, a barbiturate
b. Diazepam, a benzodiazepine
c. Midazolam, a benzodiazepine
d. Eszopiclone, a nonbenzodiazepine sleep aid
ANS: D
Eszopiclone is one of the newest prescription hypnotics to be approved for long-term use in treatment of insomnia. Barbiturates and benzodiazepines are not appropriate for long-term treatment of insomnia; midazolam is used for procedural (moderate) sedation.
A patient tells the nurse that he likes to drink kava herbal tea to help him relax. Which statement by the patient indicates that additional teaching about this herbal product is needed?a. ―I will not drink wine with the kava tea.‖
b. ―If I notice my skin turning yellow, I will stop taking the tea.‖
c. ―I will not take sleeping pills if I have this tea in the evening.‖
d. ―I will be able to drive my car after drinking this tea.‖
ANS: D
Patients should not drive after drinking this tea because it may cause sedation. Kava tea may cause skin discoloration (with long-term use). In addition, it must not be taken with alcohol, barbiturates, and psychoactive drugs.
The nurse is preparing to administer a barbiturate. Which conditions or disorders would be a contraindication to the use of these drugs? (Select all that apply.)
a. Gout
b. Pregnancy
c. Epilepsy
d. Severe chronic obstructive pulmonary disease
e. Severe liver disease
f. Diabetes mellitus
ANS: B, D, E
Contraindications to barbiturates include pregnancy, significant respiratory difficulties, and severe liver or renal disease. The other disorders are not contraindications.
The barbiturate phenobarbital is prescribed for a patient with epilepsy. While assessing the patient‘s current medications, the nurse recognizes that interactions may occur with which drugs? (Select all that apply.)
a. Antihistamines
b. Opioids
c. Diuretics
d. Anticoagulants
e. Oral contraceptives
f. Insulin
ANS: A, B, D, E
The co-administration of barbiturates and alcohol, antihistamines, benzodiazepines, opioids, and tranquilizers may result in additive CNS depression. Co-administration of anticoagulants and barbiturates can result in decreased anticoagulation response and possible clot formation. Co-administration of barbiturates and oral contraceptives can result in accelerated metabolism of the contraceptive drug and possible unintended pregnancy. There are no interactions with diuretics and insulin.
