Anticuerpos Monoclonales Para El Tx Del Cáncer Flashcards

1
Q

Rituximab

A

Blanco: CD20
Usos: linfoma no Hodgkin y leucemia crónica lifocítica (CLL)

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2
Q

Trastuzumab

A

Blanco: HER2
Usos: cáncer de mama y de estómago

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3
Q

Son los 4 anticuerpos monoclonales conjugados GITB

A

Gentuzumab ozogamicina
Ibritumomab tiuxetan
I-Tositumomab
Brentuximab vedotina

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4
Q

Gentuzumab ozogamizina

A

Blanco: CD33
Usos: leucemia mielógena aguda

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5
Q

Alentuzumab

A

Blanco: CD52
Usos: CLL

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6
Q

Ibritumomab tiuxetan

A

Blanco: CD20
Usos: linfoma no Hodgkin

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7
Q

Tositumomab

A

Blanco: CD20
Usos: linfoma no Hodgkin

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8
Q

Cetuximab

A

Blanco: EGFR
Usos: cáncer colorectal y de cabeza y cuello

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9
Q

Bevacizumab

A

Blanco: VEGF
Usos: cáncer colorectal, de pulmón de células no pequeñas, de mama, glioblastoma y de riñón

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10
Q

Panitumumab

A

Blanco: EGFR
Usos: cáncer colorectal

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11
Q

Ofatumumab

A

Blanco: CD20
Usos: CLL

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12
Q

Denosumab

A

Blanco: RANKL
Usos: cáncer extendido a hueso

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13
Q

Ipilimumab

A

Blanco: CTLA-4
Usos: melanoma

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14
Q

Brentuximab vedotina

A

Blanco: PD1
Usos: melanoma, cáncer de células claras de pulmón, cáncer de riñón y linfoma de Hodgkin

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15
Q

Atezolizumab

A

Blanco: PD-L1
Usos: cáncer de vejiga, cáncer de células claras de pulmón y carcinoma de células de Merkel

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