AntiCoagulants Cardiac Flashcards
The antidote for Heparin is
Protamine Sulfate
The antidote for Warfarin is?
Vitamin K
MOA of Heparin
Prevents the activation of thrombin, which inhibits the conversion of fibrinogen to fibrin.
MOA of Warfarin
Interferes with the production of Vitamin K
Decreases Clotting factors 7,9, and 10.
Fat soluble vitamin that aids the blood in clotting and coagulation
Vitamin K
Heparin is given in what route?
IV or SubQ
Warfarin is given?
PO
The onset of heparin is
Hella Fast Heparin
Within minutes
Short Term Therapy
Warfarin onset is?
Slow
24-72 hours
Long term Therapy
What are we monitoring in Heparin and Warfarin?
aPTT in Hep
PT/INR in War
Therapeutic Uses for Heparin and Warfarin
Prevents New Clots and prevents clots from getting bigger.
Ex A Fib
DVT
Side Effects from Heparin and Warfarin
Mild or Severe Bleeding
Examples: Bruising, petechiae, Bloody stool, and Vomiting of coffee grounds
PT Education for Heparin
SubQ in the belly
2 in from umbilicus
Do not massage
90 degree angle
PT education for Warfarin
Educate to be consistent with Vitamin K intake. Do not increase or decrease.
Examples of Vitamin K rich food are:
Liver and Green leafy vegetables.
What are some education teaching needed for patients on anti- coagulants?
AVOID
NSAIDs, Aspirin, antibiotics, alcohol
Flossing
Contact Sports
Straining Bowels
Remove Throw Rugs
Use Electric Razor
Gentle soft bristle toothbrushes
Wear Medic Alert bracelet