Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Pharmacology > Anticoagulants, Antiplatelets, Thrombolytics, Antilipidemics, And Vasodilators > Flashcards

Anticoagulants, Antiplatelets, Thrombolytics, Antilipidemics, And Vasodilators Flashcards

0
Q

Antagonist for heparin

A

Protamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

Monitor PTT and aPTT
Warfarin
Heparin

A

Heparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Does anticoagulants dissolve clots

A

No

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Interferes with clotting cascade and thrombin formation
Inhibit clot formation
Used for both arterial and venous vessel disorders

A

Anticoagulants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Name some disorders anticoagulants are used for

A 
DVT
PE
MI
Artificial heart valves
CVA
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What does heparin bind with

A

Anti thrombin III

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Low molecular weight heparins

A 
Lovenox
Fragmin
Orgaran
Innohep
Atrixtra
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Where do you inject lovenox

A

Subcu into love handles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are three things you do not do when injecting lovenox

A

Clear air bubbles
Aspirate
Massage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the black box warning or lovenox

A

Spinal/epidural hematoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How long does it take for clot to break without busting

A

Within a week or two

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Can heparin decrease or increase platelet count

A

Decrease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Lower risk of bleeding
Heparin
Lovenox

A

Lovenox

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How often do you rotate sites for lovenox

A

Every 12 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Directly prevent thrombin from contributing to the development of the fibrin clot

A

Direct thrombin inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Name some direct thrombin inhibitors

A

Acova
Angiomax
Redfludan
Iprivask

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are lab tests to monitor with warfarin

A

PT and INR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What do you want range for INR to be between

A

2-3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Warfarin

High or low protein bound

A

Highly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Antagonist for warfarin

A

Vitamin K

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Diet restrictions if you are on warfarin

A

Greens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Prevent thrombosis in arteries by suppressing platelet aggregation (keep platelets from sticking together)

A

Antiplatelets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What conditions are Antiplatelets used to treat

A

Patients with family hx of MI OR CVA
patients for prevention of MI OR CVA
Patients having TIAs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Name some Antiplatelets

A 
Persantine
Ticlid
Plavix
Pletal (vasodilator)
Aspirin
Reopro
Integrilin
Aggrastat
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Usual dosage of plavix
75 mg
25
What decreases effect of Plavix
Prilosec
26
Inhibits platelet aggregation by preventing ADP from binding with the ADP platelet receptor Has human genetic effects
Plavix
27
What pregnancy category is Plavix
B
28
Loading dose of Plavix
300 mg
29
Used as an alternative for Plavix
Effient
30
Dosing of Effient
Loading dose 60 followed by 10 mg daily
31
What is recommended to take with Effient
Aspirin
32
How much a month does Effient cost
250 a month
33
Does Effient have any poor metabolizers
No
34
A platelet inhibitor used to treat acute coronary syndrome along with aspirin Lots of drug interactions
Brilinta
35
Dose of Brilinta
90 mg Po bid
36
Patient teaching for Antiplatelets
``` Monitor for bleeding Excessive bruising Bleeding around gums Tarry stools Use soft toothbrush Use electric razor Keep apts for lab work Keep medic alert card or bracelet Check with provider before taking OTC meds or herbal preps ```
37
Clot busters Promote fibrinolytic mechanisms which destroy fiber in the clot Given within 3.5-4.5 hours of symptoms of CVA GIven within 12 hours of symptoms of MI (if PTCA not available)
Thrombolytics
38
Watch for repercussion dysrhythmias after administration for MI Antiplatelets Thrombolytics Anticoagulants
Thrombolytics
39
Name some Thrombolytics
``` Streptokinase Urokinase Activase Retavase TNKase ```
40
Thrombolytics end in
Ase
41
Drugs used to lower lipoproteins
Antilipidemics
42
Good cholesterol
HDL
43
Bad cholesterol
LDL | Chylomicrons
44
Very bad cholesterol
VLDL
45
Elevated cholesterol, triglycerides, and LDL at increased risk of
Coronary artery dx
46
Risk factors for CAD
``` Genetics Age Lifestyle Stress HTN obesity Cigarettes Get regular checkups ```
47
Nonpharmacologic methods to reduce cholesterol
Reduce saturated fats and cholesterol in diet Maintain optimum weight Implement medically supervised exercise plan Increase soluble fiber in diet Reduce or eliminate tobacco use
48
Cholesterol level 100-200 150-200 250-300
150-200
49
Triglyceride level 50-150 175-200 40-150
40-150
50
LDL level Less than75 Less than 100 Less than 150
Less than 100
51
HDL level 45-60 60-75 35-60
45-60
52
Reduce LDL cholesterol by binding with bike acids in the intestine
Bile acid sequestrants
53
Which bile acid sequestrants reduces LDL
Questran
54
Which bile acid sequestrant has fewer side effects
Colestid
55
Which bile sequestrant do you want to watch vitamin D3 level
Welchol
56
Reduce triglycerides and VLDL HIGHLY PROTEIN bound Side effects cardiac dysrhythmias, angina, thromboembolism, gallstones
Fibrates (tricor and lopid)
57
Which vitamin increases HDL, reduces VLDL and LDL
B3
58
Cholesterol absorption inhibitor works in | Small or large intestine
Small
59
Example of cholesterol absorption inhibitor
Zetia
60
HMG CoA reductase inhibitors work in
Liver to decrease cholesterol, LDL, VLDL, triglycerides, but | Slightly increases HDL
61
Best time of day to take HMG COA reductase inhibitor Morning Night
Night -bedtime
62
Which pregnancy category is HMG CoA reductase in
X
63
No more LFT monitoring after baseline, monitor for muscle aches (rhabdomyolysis)
Statins - HMG CoA inhibitors
64
Name some statins
``` Lipitor Lescol Mevacor Pravachol Zocor Crestor Livalo ```
65
Which fibrate blocks absorption
Zetia
66
Taking aspirin helps decrease flush
Nicotinic acid
67
What doesn't mix with grapefruit juice
Statins
68
Increase blood flow to extremities | Treat peripheral arterial dx (PAD, PVD) and vasospasms (Raynaud's and Buerger's)
Vasodilators
69
Side effects of Vasodilators
``` N/V Dizziness Hypotension Tachycardia Palpitations Flushing ```
70
Examples of Vasodilators
Vasodilan Cerepan Pletal Trental
71
Vasodilator that is aCtually a hemorrhagic agent
Trental
72
Three things to assess with Vasodilators
Baseline vital signs Signs of inadequate flow Pain
73
Interventions while on Vasodilators
``` Monitor vital signs Change positions slowly Be patient as it may take one and a half to three months to work Don't smoke Don't drink ```
74
Side effects of Vasodilators
Hypotension N/V/D Tachycardia

Pharmacology (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions