Anticoagulants & Antiplatelets Flashcards

1
Q

What are dental procedures that are unlikely to casue bleeding?

A
  • LA infiltration & IDB
  • BPE
  • supragingival removal of plaque, calculus and staining
  • direct or indirect restorations with supragingival margins
  • endodontics
  • impressions/pros procedures
  • fitting & adjustment of ortho appliances
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2
Q

What are dental procedures that are likely to cause bleeding on a low risk scale?

A
  • simple extractions (1-3 teeth)
  • incision and drainage of intraoral swellings
  • detailed 6PPC
  • root surface debridement
  • direct/indirect restorations with subgingival margins
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3
Q

What are dental procedures that are likely to cause bleeding on a high risk scale?

A
  • complex extractions
  • flap raising procedures (surgical extractions, periodontal surgery, periradicular surgery, crown lengthening, dental implant surgery
  • biopsy
  • gingival recontouring
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4
Q

Why do patients suffering from chronic renal failure have an increased bleeding risk?

A

associated platelet disfunction

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5
Q

Why do patients suffering from liver disease have an increased bleeding risk?

A
  • reduced production of coagulation factors
  • reduction in platelet number & function
  • alcohol excess can also result in direct bone marrow toxicity and reduced platelet numbers
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6
Q

Why do patients who have has recent or current chemotherapy or radiotherapy have an increased bleeding risk?

A

Pancytopenia including reduced platelet numbers

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7
Q

How should you assess bleeding risk in a clinical scenario?

A
  • is dental treatment required high bleeding risk
  • confirm medication & use with patient
  • find out if anticoag/antiplatelet treatment is lifelong or limited
  • ask patient about medical conditions
  • ask patient about bleeding history
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8
Q

What haemostatic measures may be required in anticoagulant / antiplatelet patients after a dental procedure that causes bleeding?

A
  • suturing
  • haemostatic packing material eg oxidized cellulose or collagen sponge
  • absorbent gauze
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9
Q

If a patient is on a time-limited course of anticoagulant/antiplatelet medication and they need extractions what should be done?

A

Delay non-urgent, invasive dental procedures where possible

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10
Q

What analgesia would you advise a pateint currently taking anticoagulant/antiplatelet medication to take?

A

Paracetamol

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11
Q

How do DOACs compare to warfarin?

A

DOACs have a rapid onset of action and a shorter half life

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12
Q

What is the half life of Apixaban?

A

12 hours

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13
Q

A patient is taking a DOAC drug and requires dental treatment that has a low risk of bleeding complications, what would you do?

A

treat without interrupting anticoagulant medication

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14
Q

A patient is taking a DOAC drug and requires dental treatment that has a high risk of bleeding complications, what would you do?

A

If apixaban/dabigatran = miss morning dose on day of treatment

Rivaroxaban/edoxaban = delay morning dose on day of treatment

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15
Q

In addition to dose delaying/skipping, what else should be arranged when performing high bleeding risk procedures on DOAC patients?

A
  • plan treatment early in day to allow for monitoring/managine any bleeding complications
  • consider carrying out treatments in staged manner over separate visits
  • strongly consider suturing and packing
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16
Q

How long after treatment do DOAC patients need to wait before taking their delayed dose?

A

Minimum 4 hours

17
Q

What should the INR level for a warfarin patient be in order for you to be able to treat them?

A

INR below 4 (24 hours)

18
Q

A patient is taking single/dual antiplatelet drugs and requires dentsl treatment that can cause bleeding what should you do?

A

Treat without interrupting medication

19
Q

What drugs prescribed by dentists should be avoided in patients taking apixaban?

A
  • NSAIDs
  • clarithromycin
  • carbamazepine (reduces plasma concentration of apixaban)