Anticoagulants Flashcards
Heparin : Drug Names
Unfractionated Heparin (Heparin)
Low Molecular Weight Heparin LMWH (Lovenox)
Heparin : Reason for Taking
prophylactically to prevent clots in pts with:
MI
a fib
CVA
post stent
implanted devices
Heparin : Action
inhibits clot formation (Ila (thrombin))
Lovenox works on factor Xa
Heparin : Contraindications
recent surgery
GI bleeds
PUD
Heparin : Adverse Reactions
Heparin-Induced Thrombocytopenia (HIT)
excessive bleeding
brusing
Heparin : Routes
SQ
IV
Vitamin K Factor : Drug Names
Warfarin (Coumadin)
Warfarin : Reason for Taking
long term management of:
MI
a fib
any implantable devices
Warfarin : Action
inhibits production of vitamin K dependent clotting factors
Warfarin : Contraindications
recent surgeries
GI bleeds
PUD
many drug interactions:
ginger
ginseng
ginkgo
Warfarin : Adverse Reactions
bleeding
purple toe syndrome
warfarin toxicity
Warfarin : Routes
PO
Factor Xa : Drug Names
Rivaroxaban (Xarelto)
Fondaparinux (Arixtra)
Apixaban (Eliquis)
Factor Xa : Reason for Taking
prevent CVA in patients with a fib, post-op ortho surgeries
Hx of DVT or PE - help avoid recurrence
Factor Xa : Action
inhibits factor Xa production
Factor Xa : Contraindications
NSAIDs
recent surgery
GI bleeds
PUD
Factor Xa : Adverse Reactions
peripheral edema
bruising
bleeding
dizziness
Factor Xa : Routes
PO
Antiplatelet : Drug Names
Aspirin (ASA)
Clopidogrel (Plavix)
Antiplatelet : Reason for Taking
post:
CVA
MI
stent placement
Antiplatelet : Action
make platelets slicky so they do not adhere to BV walls
Antiplatelet : Contraindications
amiodarone
PPI
calcium channel blockers
NSAIDs
Antiplatelet : Adverse Reactions
bleeding:
gums
nosebleed
puncture sites
surgical sites
hematuria
Antiplatelet : Routes
PO
ASA rectal
Antihyperlipidemic - Bile Acid Sequestrants : Drug Names
Cholestyramine (Questran)
Antihyperlipidemic - BAS : Reason for Taking
hyperlipidemia (elevated lipids)
Antihyperlipidemic - BAS : Action
prevents absorption of bile acids from the small intestine
Antihyperlipidemic - BAS : Contraindications
bowel obstructions
phenylketonuria (PKU)
Antihyperlipidemic - BAS : Adverse Reactions
constipation
heartburn
loss of appetite
headache
vitamin deficencies
Antihyperlipidemic - BAS : Routes
PO
Antihyperlipidemic - HMG CoA Inhibitors : Drug Names
Simvastatin (Zocor)
Atorvastatin (Lipitor)
Rosuvastatin (Crestor)
HMG CoA Inhibitors: Reason for Taking
hyperlipidemia (elevated lipids)
HMG CoA Inhibitors : Action
inhibits the HMG coA enzymes which help make cholesterol
HMG CoA Inhibitors : Contraindications
grapefruit
some cardiac drugs
antibiotics
HMG CoA Inhibitors : Adverse Reactions
GI distress
rashes
muscle pain
liver problems
HMG CoA Inhibitors : Routes
PO