Anticoagulants Flashcards

1
Q

Heparin : Drug Names

A

Unfractionated Heparin (Heparin)
Low Molecular Weight Heparin LMWH (Lovenox)

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1
Q

Heparin : Reason for Taking

A

prophylactically to prevent clots in pts with:
MI
a fib
CVA
post stent
implanted devices

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2
Q

Heparin : Action

A

inhibits clot formation (Ila (thrombin))
Lovenox works on factor Xa

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3
Q

Heparin : Contraindications

A

recent surgery
GI bleeds
PUD

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4
Q

Heparin : Adverse Reactions

A

Heparin-Induced Thrombocytopenia (HIT)
excessive bleeding
brusing

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5
Q

Heparin : Routes

A

SQ
IV

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6
Q

Vitamin K Factor : Drug Names

A

Warfarin (Coumadin)

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7
Q

Warfarin : Reason for Taking

A

long term management of:
MI
a fib
any implantable devices

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8
Q

Warfarin : Action

A

inhibits production of vitamin K dependent clotting factors

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9
Q

Warfarin : Contraindications

A

recent surgeries
GI bleeds
PUD
many drug interactions:
ginger
ginseng
ginkgo

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10
Q

Warfarin : Adverse Reactions

A

bleeding
purple toe syndrome
warfarin toxicity

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11
Q

Warfarin : Routes

A

PO

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12
Q

Factor Xa : Drug Names

A

Rivaroxaban (Xarelto)
Fondaparinux (Arixtra)
Apixaban (Eliquis)

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13
Q

Factor Xa : Reason for Taking

A

prevent CVA in patients with a fib, post-op ortho surgeries
Hx of DVT or PE - help avoid recurrence

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14
Q

Factor Xa : Action

A

inhibits factor Xa production

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15
Q

Factor Xa : Contraindications

A

NSAIDs
recent surgery
GI bleeds
PUD

16
Q

Factor Xa : Adverse Reactions

A

peripheral edema
bruising
bleeding
dizziness

17
Q

Factor Xa : Routes

18
Q

Antiplatelet : Drug Names

A

Aspirin (ASA)
Clopidogrel (Plavix)

19
Q

Antiplatelet : Reason for Taking

A

post:
CVA
MI
stent placement

20
Q

Antiplatelet : Action

A

make platelets slicky so they do not adhere to BV walls

21
Q

Antiplatelet : Contraindications

A

amiodarone
PPI
calcium channel blockers
NSAIDs

22
Q

Antiplatelet : Adverse Reactions

A

bleeding:
gums
nosebleed
puncture sites
surgical sites
hematuria

23
Q

Antiplatelet : Routes

A

PO
ASA rectal

24
Q

Antihyperlipidemic - Bile Acid Sequestrants : Drug Names

A

Cholestyramine (Questran)

25
Q

Antihyperlipidemic - BAS : Reason for Taking

A

hyperlipidemia (elevated lipids)

26
Q

Antihyperlipidemic - BAS : Action

A

prevents absorption of bile acids from the small intestine

27
Q

Antihyperlipidemic - BAS : Contraindications

A

bowel obstructions
phenylketonuria (PKU)

28
Q

Antihyperlipidemic - BAS : Adverse Reactions

A

constipation
heartburn
loss of appetite
headache
vitamin deficencies

29
Q

Antihyperlipidemic - BAS : Routes

30
Q

Antihyperlipidemic - HMG CoA Inhibitors : Drug Names

A

Simvastatin (Zocor)
Atorvastatin (Lipitor)
Rosuvastatin (Crestor)

31
Q

HMG CoA Inhibitors: Reason for Taking

A

hyperlipidemia (elevated lipids)

32
Q

HMG CoA Inhibitors : Action

A

inhibits the HMG coA enzymes which help make cholesterol

33
Q

HMG CoA Inhibitors : Contraindications

A

grapefruit
some cardiac drugs
antibiotics

34
Q

HMG CoA Inhibitors : Adverse Reactions

A

GI distress
rashes
muscle pain
liver problems

35
Q

HMG CoA Inhibitors : Routes