Anticoagulants Flashcards

1
Q

MOA Heparin & low molecular weight heparin

enoxaparin, Lovenox

A

Prevents clotting by activating Antithrombin- indirectly inactivates thrombin & factor Xa

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2
Q

Side Effects of ALL anticoagulants

A

BLEEDING

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3
Q

Nursing Considerations of Heparin

A

Starts working Quickly

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4
Q

Adverse effects of Heparin

A

Bleeding, hematoma, anemia, thrombocytopenia

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5
Q

Indications of Enoxaparin (Lovenox)

A

given prophylaxis & treatment

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6
Q

Adverse Effects of Enoxaparin (Lovenox)

A

bleeding, thrombocytopenia

can cause HIT

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7
Q

MOA of Warfarin (Coumadin)

A

prevents the synthesis of four coagulation factors

VII, IX, X, prothrombin

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8
Q

Adverse Effects of Warfarin (Coumadin)

A

bleeding, lethargy, muscle pain, purple toes

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9
Q

MOA of Apixaban (Eliquis) & Rivaroxabean (Xarelto)

A

direct inhibitor of factor Xa

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10
Q

Adverse effects of Apixaban (Eliquis) & Rivaroxabean (Xarelto)

A

bleeding, hematoma, dizziness, rash, gastrointestinal distress, peripheral edema

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11
Q

Aspirin (as anti-platelet)

A

blocks prostaglandin synthesis through the COX enzyme pathways

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12
Q

Side effects of Aspirin

A

n/v, drowsiness/confusion, bleeding

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13
Q

MOA of Clopidogrel (Plavix) & Ticagrelor (Brilinta)

A

antiplatelet ADP inhibitor

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14
Q

Side effects of Clopidogrel & Ticagrelor

A

chest pain, edema, flu-like symptoms, abdominal pain, diarrhea, nausea, epistaxis, rash, pruritus

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15
Q

Thrombin Inhibitors

A

inhibit thrombin (factor lla)

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16
Q

Adverse Effects of thrombin inhibitors

A

bleeding