Anticoagulant Dosing

Question 1

loading dose for unfractionated heparin (UFH) in UA/NSTEMI

Answer 1

60units/kg bolus

Question 2

maintenance dose of UFH in UA/NSTEMI

Answer 2

12 units/kg/hr for 48 hours or until PCI

Question 3

UFH loading dose in STEMI

Answer 3

fibrinolytic 60 units/kg bolus

Question 4

UFH maintenance dose in STEMI

Answer 4

12 units/kg/hr until PCI

Question 5

UFH dosing in PCI

Answer 5

with GPIIb/IIIa 50-70 units/kf bolus

without GPIIb/IIIa: 70-100 units-kg IV bolus

until PCI

Question 6

enoxaparin dosing for UA/NSTEMI

Answer 6

1mg/kg every 12 hours adjusted for CrCl less than 30ml/min until discharge or PCI (up to 8 days)

Question 7

enoxaparin dosing for STEMI

Answer 7

less than 75 years: 30mg IV then 1mg/kg every 12 hours

older than 75 years: .75mg/kg every 12 hours

until discharge or PCI (up to 8 days)

Question 8

enoxaparin dosing for PCI

Answer 8

administer additional 0.3mg/kg IV if last dose is 8-12 hours before PCI

Question 9

bivalirudin indication

Answer 9

only to be used in patients with planned early invasive strategy

Question 10

fondaparinux contraindication

Answer 10

CrCl <30ml/min