ANTICHOLINERGIC Flashcards
DOCUMENTATION
CLINICAL FEATURES
“Hot as a hare, blind as a bat, dry as a bone, mad as a hatter, fast as a fox, red as a beet, full as a flask”
Hyperthermia
Mydriasis
Dry Mucous Membranes
Altered Mental Status / Agitation
Tachycardia
Warm flushed Skin
Urinary Retention
Slowed GI Motility
MANAGEMENT
Cooling if hyperthermic
Decompress bladder if necessary for urinary retention
Isotonic IV fluids
Benzodiazepines
Physostigmine, diagnostically or therapeutically, to reverse anticholinergic-induced delirium:
0.5 mg increments over 3 to 5 min in adults to a maximum of 2 mg, 0.02 mg/kg (max 0.5 mg/dose) in children
redosed in 30 to 90 min
Caution is advised in patients with QRS widening, bradycardia, or hypotension, because these are evidence of additional potentially life-threatening toxic effects.
