Antibody & Disease Association Flashcards by Danny Tudor

Q

RF

A

Rheumatic Disease

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Q

CCP

A

RA (Sensitive + Specific)

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Q

ANA / FANA

A

SLE (Sensitive), Sjogren, Myositis, Lupus,

Old Age, + FMHx

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Q

ACH

A

Sjogren

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Q

Sc70 / Topo

A

Diffuse Scleroderma (Specific + Sensitive)

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Q

Centromere

A

CREST (Specific + Sensitive)

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Q

RNA-Poly 3

A

Scleroderma Renal Crisis

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Q

Th

A

Scleroderma PAH

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Q

PM-Sci

A

Systemic Scleroderma, Polymyositis

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Q

PDGF-R

A

Scleroderma

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Q

MMP

A

Scleroderma

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Q

Histone

A

Rx-SLE

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Q

Ro/SSA (ENA)

A

Sjogren, SLE (Neonatal, SCLE)

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Q

La/SSB (ENA)

A

Sjogren, SLE (Neonatal)

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Q

Sm

A

SLE (Specific, but not equal to Disease Activity)

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Q

U1RNP

A

MCTD (mixed connective tissue disease)

Q

ds-DNA

A

Renal SLE (Equal to Disease Activity)

Q

Jo1 / Synthetase

A

Inflammatory Myopathy (Synthetase Syndrome)

Q

SRP

A

Inflammatory Myopathy ( Decrease Prog)

Q

Mi-2

A

Inflammatory Myopathy (Increase Prog)

Q

P-Lipid (LA/aCL)

A

HyperCoag anticardiolipin antibodies = aCL

SLE (Miscarriage, Neuro) lupus anticoagulant = LA

Q

cANCA

A

Granulomatosis with polyangiitis

Wegener’s

Q

pANCA

A

Micro. Polyangitis, Churg-Strauss, IBD

Q

Serial ESR/CRP

A

RA