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Autoimmune Disease & Antibody Tested > Antibody > Flashcards

Antibody Flashcards

1
Q

Antiphospholipid syndrome

A

Anti B2GP1

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2
Q

Autoimmune hepatitis

A

F-actin reactive smooth muscle

Antinuclear

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3
Q

Celiac

A

Anti-tissue Transglutaminase (anti-tTG) (IgA)

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4
Q

Graves

A

Anti-thyroid peroxidase antibody (anti-TPO)

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5
Q

Guillain-Barré

A

Gangliosides antibodies

Anti-glycolipid antibodies

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6
Q

Hashimoto thyroiditis

A

Anti-thyroid peroxidase

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7
Q

Ulcerative colitis

A

pANCA Perinuclear anti-neutrophil cytoplasmic antibody (60-80% pts)
(Clinical dx)

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8
Q

Crohn’s

A

ASCA Saccharomyces cerevisiae antibodies IgG and IgA

60-70% G, 35% A

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9
Q

Rapidly progressing Crohn’s

A

Anti-Omp C (e.coli antibodies)

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10
Q

Multiple sclerosis

A

Two or more bands of IgG in CSF

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11
Q

Myasthenia Gravis

A

Acetylcholine receptor (AChR) (90%)
Anti-muscle-specific kinase (AMuSK) (50-70%)
Anti-striated muscle (80% pts w/ big thymus gland)

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12
Q

Pernicious anaemia

A

Anti-Parietal cell

Intrinsic factor

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13
Q

Primary billary cirrhosis

A

Anti mitochondria

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14
Q

Reactive arthritis

A

HLA-B27 antigen

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15
Q

Rheumatoid arthritis

A

(Rheumatoid factor)

Anti-cyclic citrullinated peptide (anti-CCP)

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16
Q

Juvenile rheumatoid arthritis

A

Antinuclear (ANA)

Rheumatoid factor, ESR, CRP

17
Q

Sarcoidosis

A

RF, ANA, ~anti-dsDNA

18
Q

Scleroderma

A

ANA
Scl-70 (scleroderma antibody) 20-60%
Centromere (ACA) 60-80 in pts w/ limited cutaneous scleroderma

19
Q

Sjögren syndrome

A

ANA
Anti-sjogrensyndrome antibodies
RF may be positive

20
Q

SLE

A

ANA
Anti-Sm (smith) (usuallu only seen in those w/ SLE)
Anti-dsDNA

21
Q

Vasculitis

A

Anti-neutrophil cytoplasmic (ANCA)

22
Q

Good pastures

A

Anti glomerular basement membran

23
Q

Psoriasis

A

ANA

Anti-dsDNA

24
Q

Wegener’s granulomatosis

A

ANCAs

Autoimmune Disease & Antibody Tested (1 decks)

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