antibodies and secondary immune response Flashcards
Neutralisation
Antibody surround pathogen and bind to it, prevents the pathogen from entering host cells thereby neutralising them
agglutination
Many antibodies bind to many antigens in one space and clump together, thereafter a phagocyte carries out phagocytosis on a whole ‘clump’
How do antitoxins help to protect cells?
do antitoxins help to protect cells?
Antibodies combine with toxins secreted by bacteria to neutralise them e.g. tetanus
Primary immune response
Antibodies are produced several days after the initial exposure to the pathogen. The immune response is relatively small
Plasma cells do not live for very long
Antibodies that they make will eventually break down
Both t and b cells will form memory cells
Will circulate in both the blood and lymph
Patrol around the body for that specific antigen
Secondary immune response
A second exposure to the same antigen activates antigen-specific memory cells
Stimulate a larger, faster and longer-lived secondary immune response
More rapid and concentration of the antibodies produced is significantly more than the primary immune response
Colonal selection occurs faster
Memory b lymphocytes are activated and divide into plasma cells that produce the antibody required
Memory t lymphocytes are activated and divide into t killer cells to destroy cells infected with the antigen
All happens before you show any symptoms – completely unaware