Antibodies Flashcards
1
Q
Rheumatoid factor
A
- Rheumatoid arthritis (70%)
- Sjogrens (100%)
- Felty’s (100%)
- Infective Endocarditis (50%)
2
Q
ANA
A
- SLE (>95%)
- Autoimmune Hepatitis (75%)
- Sjogrens (70%)
3
Q
AMA
A
- PBC
4
Q
pANCA
A
- UC
- PSC
5
Q
Anti-centromere (ACA)
A
CREST
6
Q
Anti-CCP
A
- Rheumatoid arthritis
7
Q
Anti-Jo
A
Polymyositis
Dermatomyositis
8
Q
Anti-dsDNA
A
SLE
9
Q
Anti Smooth Muscle (ASMA)
A
Autoimmune Hepatitis
10
Q
HLA-A3
A
Haemochromatosis
11
Q
HLA-B51
A
Behcet’s
12
Q
HLA-B27
A
- Psoriasis
- IBD
- Ankylosing Spondylitis
- Reactive Arthritis
- Acute anterior uveitis
13
Q
HLA-DQ2/DQ8
A
Coeliac’s
14
Q
HLA-DR2
A
- Narcolepsy
- Goodpasture’s
15
Q
HLA-DR3
A
- Dermatitis Herpetiformis
- Sjogren’s
- PBC
- T1DM (weaker link than DR4)
16
Q
HLA-DR4
A
- T1DM (stronger link than DR3)
- Rheumatoid arthritis
17
Q
Anti-Ro
A
- Sjogren’s
18
Q
Anti Scl-70
A
Diffuse cutaneous Scleroderma
19
Q
LKM antibody
A
aka Liver kidney microsomal antibody
Autoimmune hepatitis
