Antibodies Flashcards

0
Q

WHat are the effector molecules of humoral immunity?

A

Antibodies

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1
Q

What does CD3 do?

A

mediates signal transduction functions from TCRs (T cell receptors) upon binding antigen from the MHC of an APC

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2
Q

Fab Region

A

The portion of an antibody that contains a whole light chain, attached to the V and C domains of the heavy chain; this is the portion responsible for antigen recognition and antigen binding. (Fab = fragment, antigen binding)

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3
Q

IgA
Secreted form?
Funciton

A

Secreted ass a dimer

fx = mucosal immunity

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4
Q

IgD
Secreted form?
Fx?

A

No secreted form

Fx= naive B cell antigen receptor

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5
Q

IgE
Secreted form?
Fx?

A

Secreted ass monomer

Fx= mast cell activation (hypersensitivity rxn) + parasite defense

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6
Q

IgG
Secreted form?
Fx?

A

Secreted as monomer,
fx= opsonization, complement activation, ab dependant cell-mediated cytotoxicity, neonate immunity, B cell feedback inhibition

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7
Q

IgM
Secreted?
Fx=

A

Secreted as Pentamer

fx= Naive B cell antigen receptor, complement activation

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