Antibodies Flashcards

1
Q

Which diseases can cause a positive Anti-Ro?

A

SLE
Sjogren’s

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2
Q

Which disease can cause a positive anti-La?

A

Sjogrens

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3
Q

Which disease can cause a positive anti-centromere?

A

CREST

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4
Q

Which disease can cause a positive anti-dsDNA?

A

SLE

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5
Q

Which disease can cause a positive anti-Jo?

A

Inflammatory myopathy

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6
Q

Which disease can cause a positive anti-Smith?

A

SLE

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7
Q

Which disease can cause a positive anti-Scl-70?

A

Systemic sclerosis

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8
Q

Which diseases can cause a positive ANA?

A

Primary biliary cirrhosis
SLE
Sjogren’s
CREST

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9
Q

Which disease can cause a positive anti-transglutaminase antibodies?

A

Coeliacs

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10
Q

Which disease can cause a positive anti-CCP?

A

Rheumatoid arthritis

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11
Q

Which disease can cause a positive anti-thrombin antibodies?

A

SLE

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12
Q

Which disease can cause a positive antiphospholipid antibodies?

A

Antiphospholipid syndrome

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13
Q

Which disease can cause a positive c-ANCA?

A

Granulomatosis with polyangiitis

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14
Q

Which diseases can cause a positive p-ANCA?

A

Microscopic polyangiitis
Eosinophilic granulomatosis with polyangiitis
Systemic vasculitides

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15
Q

Which disease can cause a positive rheumatoid factor?

A

Rheumatoid arthritis

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16
Q

Which disease can cause a positive anti-smooth muscle antibody?

A

Autoimmune hepatitis

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17
Q

Which disease can cause a positive anti-mitochondrial antibody?

A

Primary biliary cirrhosis

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18
Q

Which disease can cause a positive anti-AChR?

A

Myasthenia gravis

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18
Q

Which disease can cause a positive anti-MUSK?

A

Myasthenia gravis

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19
Q

Which disease can cause a positive anti-VGCC?

A

Lambert-Eaton myasthenic syndrome

20
Q

Which diseases can cause a positive anti-TPO antibodies?

A

Hashimoto’s thyroiditis
Graves’ disease

21
Q

Which disease can cause a positive anti-NMDA receptor?

A

Anti-NMDA receptor encephalitis

22
Q

Which disease can cause a positive anti-glomerular basement membrane?

A

Goodpasture syndrome

23
Q

Which disease can cause a positive anti-parietal cell?

A

Pernicious anaemia

24
Q

Which disease can cause a positive anti-intrinsic factor?

A

Pernicious anaemia

25
Q

Which disease can cause a positive anti-phospholipase A2 receptor?

A

Membranous nephropathy

26
Q

Which antibodies can be positive in SLE?

A

Antinuclear antibodies:
Anti-Ro
Anti-dsDNA
Anti-smith

27
Q

Which antibodies can be positive in Sjogren’s?

A

Antinuclear antibodies:
Anti-Ro
Anti-La

28
Q

Which antibody can be positive in inflammatory myopathy?

A

Anti-Jo1

29
Q

Which antibody can be positive in CREST syndrome?

A

Anti-centromere

30
Q

Which antibodies can be positive in systemic sclerosis?

A

Antinuclear antibodies:
Anti-Scl-70

31
Q

Which antibodies can be positive in primary biliary cirrhosis?

A

Antinuclear antibodies
Anti-mitochondrial antibody

32
Q

Which antibody can be positive in coeliac disease?

A

Anti-transglutaminase (anti-tTG)

33
Q

Which antibodies can be positive in rheumatoid arthritis?

A

Anti-CCP
Rheumatoid factor

34
Q

Which antibody can be positive in antiphospholipid syndrome?

A

Antiphospholipid antibodies

35
Q

Which antibodies can be positive in granulomatosis with polyangiitis?

A

c-ANCA
p-ANCA

36
Q

Which antibody can be positive in microscopic polyangiitis?

A

p-ANCA

37
Q

Which antibody can be positive in eosinophilic granulomatosis with polyangiitis?

A

p-ANCA

38
Q

Which antibody can be positive in systemic vasculitides?

A

p-ANCA

39
Q

Which antibody can be positive in autoimmune hepatitis?

A

Anti-smooth muscle antibody

40
Q

Which antibodies can be positive in myasthenia gravis?

A

Anti-AChR
Anti-MUSK

41
Q

Which antibody can be positive in Lambert-Eaton myasthenic syndrome?

A

Anti-VGCC

42
Q

Which antibodies can be positive in Hashimoto’s thyroiditis?

A

Anti-TPO
Anti-thyroglobulin

43
Q

Which antibodies can be positive in Graves’ disease?

A

Anti-TPO
Anti-thyrotropin receptor

44
Q

Which antibody can be positive in anti-NMDA receptor encephalitis?

A

Anti-NMDAr

45
Q

Which antibody can be positive in Goodpasture syndrome?

A

Anti-glomerular basement membrane

46
Q

Which antibodies can be positive in pernicious anaemia?

A

Anti-parietal cell
Anti-intrinsic factor

47
Q

Which antibody can be positive in membranous nephropathy?

A

Anti-phospholipase A2 receptor