Antibodies Flashcards
Which diseases can cause a positive Anti-Ro?
SLE
Sjogren’s
Which disease can cause a positive anti-La?
Sjogrens
Which disease can cause a positive anti-centromere?
CREST
Which disease can cause a positive anti-dsDNA?
SLE
Which disease can cause a positive anti-Jo?
Inflammatory myopathy
Which disease can cause a positive anti-Smith?
SLE
Which disease can cause a positive anti-Scl-70?
Systemic sclerosis
Which diseases can cause a positive ANA?
Primary biliary cirrhosis
SLE
Sjogren’s
CREST
Which disease can cause a positive anti-transglutaminase antibodies?
Coeliacs
Which disease can cause a positive anti-CCP?
Rheumatoid arthritis
Which disease can cause a positive anti-thrombin antibodies?
SLE
Which disease can cause a positive antiphospholipid antibodies?
Antiphospholipid syndrome
Which disease can cause a positive c-ANCA?
Granulomatosis with polyangiitis
Which diseases can cause a positive p-ANCA?
Microscopic polyangiitis
Eosinophilic granulomatosis with polyangiitis
Systemic vasculitides
Which disease can cause a positive rheumatoid factor?
Rheumatoid arthritis
Which disease can cause a positive anti-smooth muscle antibody?
Autoimmune hepatitis
Which disease can cause a positive anti-mitochondrial antibody?
Primary biliary cirrhosis
Which disease can cause a positive anti-AChR?
Myasthenia gravis
Which disease can cause a positive anti-MUSK?
Myasthenia gravis
Which disease can cause a positive anti-VGCC?
Lambert-Eaton myasthenic syndrome
Which diseases can cause a positive anti-TPO antibodies?
Hashimoto’s thyroiditis
Graves’ disease
Which disease can cause a positive anti-NMDA receptor?
Anti-NMDA receptor encephalitis
Which disease can cause a positive anti-glomerular basement membrane?
Goodpasture syndrome
Which disease can cause a positive anti-parietal cell?
Pernicious anaemia
Which disease can cause a positive anti-intrinsic factor?
Pernicious anaemia
Which disease can cause a positive anti-phospholipase A2 receptor?
Membranous nephropathy
Which antibodies can be positive in SLE?
Antinuclear antibodies:
Anti-Ro
Anti-dsDNA
Anti-smith
Which antibodies can be positive in Sjogren’s?
Antinuclear antibodies:
Anti-Ro
Anti-La
Which antibody can be positive in inflammatory myopathy?
Anti-Jo1
Which antibody can be positive in CREST syndrome?
Anti-centromere
Which antibodies can be positive in systemic sclerosis?
Antinuclear antibodies:
Anti-Scl-70
Which antibodies can be positive in primary biliary cirrhosis?
Antinuclear antibodies
Anti-mitochondrial antibody
Which antibody can be positive in coeliac disease?
Anti-transglutaminase (anti-tTG)
Which antibodies can be positive in rheumatoid arthritis?
Anti-CCP
Rheumatoid factor
Which antibody can be positive in antiphospholipid syndrome?
Antiphospholipid antibodies
Which antibodies can be positive in granulomatosis with polyangiitis?
c-ANCA
p-ANCA
Which antibody can be positive in microscopic polyangiitis?
p-ANCA
Which antibody can be positive in eosinophilic granulomatosis with polyangiitis?
p-ANCA
Which antibody can be positive in systemic vasculitides?
p-ANCA
Which antibody can be positive in autoimmune hepatitis?
Anti-smooth muscle antibody
Which antibodies can be positive in myasthenia gravis?
Anti-AChR
Anti-MUSK
Which antibody can be positive in Lambert-Eaton myasthenic syndrome?
Anti-VGCC
Which antibodies can be positive in Hashimoto’s thyroiditis?
Anti-TPO
Anti-thyroglobulin
Which antibodies can be positive in Graves’ disease?
Anti-TPO
Anti-thyrotropin receptor
Which antibody can be positive in anti-NMDA receptor encephalitis?
Anti-NMDAr
Which antibody can be positive in Goodpasture syndrome?
Anti-glomerular basement membrane
Which antibodies can be positive in pernicious anaemia?
Anti-parietal cell
Anti-intrinsic factor
Which antibody can be positive in membranous nephropathy?
Anti-phospholipase A2 receptor