Antibodies

Question 1

Anti-Ro

Answer 1

SLE

Sjogren’s

Question 2

Anti-La

Answer 2

Sjogren’s

Question 3

Anti-centromere

Answer 3

CREST (limited cutaneous systemic sclerosis)

Question 4

Anti-dsDNA

Answer 4

SLE

Question 5

Anti-Jo1

Answer 5

Inflammatory myopathy (Dermatomyositis)

Question 6

Anti-Smith

Answer 6

SLE

Question 7

Anti-Scl-70

Answer 7

Diffuse systemic sclerosis

Question 8

Anti-histone

Answer 8

SLE

Drug-induced LE

Question 9

Anti-p62, anti-sp100, anti-glycoprotein210, anti-mitochondrial

Answer 9

Primary biliary cirrhosis

Question 10

Anti-tTG

Answer 10

Coeliac

Question 11

Anti-eTG

Answer 11

Dermatitis herpetiformis

Question 12

Anti-actin

Answer 12

Coeliac

Question 13

Anti-CCP, RF

Answer 13

Rheumatoid arthritis

Question 14

Anti-thrombin

Answer 14

SLE

Question 15

Anti-phospholipid

Answer 15

Anti-phospholipid syndrome

Question 16

c-ANCA

Answer 16

Granulomatosis with polyangitis

Question 17

p-ANCA

Answer 17

Microscopic polyangitis
Eosinophilic granulomatosis with polyangitis
Systemic vasculitides (non-specific)

Question 18

Anti-smooth muscle

Answer 18

Chronic autoimmune hepatitis

Question 19

Anti-SRP

Answer 19

Polymyositis

Question 20

Anti-AChR, anti-MUSK

Answer 20

Myasthenia gravis

Question 21

Anti-VGCC

Answer 21

Lambert Eaton myasthenia syndrome

Question 22

Anti-thyroglobulin, anti-TPO

Answer 22

Hashimoto’s

Question 23

Anti-TSH, anti-TPO

Answer 23

Grave’s

Question 24

Anti-desmoglein

Answer 24

Pemphis vulgaris

Question 25

Anti-hemidesmosome

Answer 25

Bullous pemphigoid

Question 26

Anti-glomerular basement membrane (BM)

Answer 26

Goodpasture’s

Question 27

Anti-phospholipase

Answer 27

Membranous encephalopathy

Question 28

Anti-parietal cell, anti-intrinsic factor

Answer 28

Pernicious anaemia