Antibiotika Flashcards

1
Q

NAG —> NAM

Hemmer?

A

Fosfomycin

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2
Q

PBP = Transpeptidasen

Hemmer?

A

Beta Lactame

Hemmen transpeptidierung bei murinsynthese

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3
Q

Penicillinasen sind was?

A

Plasmid

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4
Q

Wie behandelt man MSSA?

A

Methicillin

Weil S. aureus Penicillin G resistent ist

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5
Q

Warum ist MRSA resistent gegenüber Methicillin?

A

Wegen mecA Gen, chromosomal

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6
Q

What about Strepto. Pneumoniae?

A

Reduzierte penicillin Empfindlichkeit

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7
Q

Es gibt 3 arten von beta lactam resistenz bei gram + bakterien

A

Look at next card

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8
Q

Beta lactamase vorkommen and ihre wirksame antibiotika

A
  1. S. Aureus
    Koagulase neg. staphs
  2. Penicillinase feste antibiotika (= oxacillin, cephalosporine) oder penicillin + beta lactamase inhibitoren
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9
Q

Bakterien mit mecA gen vorkommen and ihre wirksame antibiotika

A
  1. MRSA und Koagulase neg. staphs

2. Glykopeptide, linezolid, daptomycin

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10
Q

Verringerte affinität bakterien (gegenüber penicillin) vorkommen and ihre wirksame antibiotika

A
  1. Pneumokokken

2. Cephalosporin 3. Gen, glykopeptide

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11
Q

Beta lactamaseinhibitoren werden immer mit einem beta lactam kombiniert. Nenne beispiele für beta lactamaseinhibitoren

A

Clavulansäure
Sulbactam
Tazobactam

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12
Q

Oralpenicillin wirksamkeit

A

Gram + sehr wirksam
Enterobaktr unwirksam

Beta lactamase empfindlich

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13
Q

Aminopemicilline wirksamkeit

A

Gram neg. stäbchen (enterobakt, haemoph influenzae)

Beta lactamase empfindlich

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14
Q

Isoxacylpenicilline (flucolaxacillin) oral

A

Penicillase feste penicilline

Staphylokokken penicilline

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15
Q

Acylaminopenicilline (p) piperacillin

A

Im gram neg. (pseudomonas aerigonosa)

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