Antibiotics: Disease focus Flashcards
How would you treat a mild skin and soft tissue infection?
Oral Flucloxacillin 500mg-1g qid 7-10 days
How would you treat severe sepsis of unknown origin?
IV Pip/taz 4.5g plus Vancomycin load than 1.5g bd Consider adding stat gentamicin IV if severe Use meropenem if high risk
How would you treat a severe community acquired pneumonia?
IV Ceftriaxone 1g daily or BD IV Azithromycin 500mg daily
How would you treat a moderate pyelonephritis?
IV Ceftriaxone 1g daily OR IV amoxycillin 2g qid plus gentamicin 5mg/kg
How would you treat a severe hospital acquired pneumonia?
IV Piperacillin and tazobactam 4.5g qid
How would you treat a severe pyelonephritis?
IV pip/taz 4.5g Consider IV stat gentamicin 5mg/kg
How would you treat intravascular catheter related sepsis?
IV Pip/Taz 4.5g qid plus IV Vancomycin load then 1.5g bd Consider adding meropenem if known colonisation with resistant bacteria or recent travel to high risk area Consider adding anti-fungal if high risk eg prolonged abx use, prolonged IV access (TPN)
How would you treat a moderate intra-abdominal infection?
IV Ceftriaxone 1g plus metronidazole 500mg bd or IV Amoxycillin, Metronidazole plus gentamicin
How would you treat a severe community acquired pneumonia in someone who is anaphylactic to penicillin?
IV Moxifloxacin 400mg daily
How would you treat necrotising fasciitis?
IV Meropenem 1g tds IV Vancomycin load then 1.5g bd IV Clindamycin 600mg tds
How would you treat a mild intra-abdominal infection?
Oral Amoxicillin / Clavulanate 875/125mg bd 7 days
How would you treat a severe intra-abdominal infection?
IV Piperacillin / Tazobactam 4.5g
How would you treat a severe skin and soft tissue infection?
IV Piperacillin / Tazobactam 4.5g qid plus Vancomycin load then 1.5g bd
How would you treat a moderate hospital acquired pneumonia?
IV Ceftriaxone 1g daily
How would you treat cystitis?
Oral Trimethoprin 300mg daily OR Oral Amoxycillin/Clavulanate 875/125mg bd OR Oral Cephalexin 500mg bd 5 days in women, 7 days in men
