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Disease N Disease > Antibiotics by class > Flashcards

Antibiotics by class Flashcards

1
Q

reduce peptidoglycan synthesis?

A

Vancomycin
Bacitracin (topical)
Fosfomycin

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2
Q

What kind of antibiotic reduces cross linking?

A

Beta-lactams

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3
Q

What is Penicillin G and V

A

G is used intravenously
V is acid stabilized for oral use

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4
Q

Antistaphylococcal penicillins?

A

Oxacillin
Nafcillin
Difloxacillin

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5
Q

Amino penicillins?

A

Amoxicillin
Ampicillin

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6
Q

Antipseudomonal penicillin?

A

Piperacillin

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7
Q

Beta-Lactamase inhibitors?

A

Clavulanate
Sulbactam
Tazobactam
Avibactam

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8
Q

What is amoxicillin + clavulanate?

A

Augmentin

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9
Q

What is ampicillin + sulbactim?

A

Unisyn

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10
Q

What is piperacillin + tazobactrim?

A

Zosyn

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11
Q

1st gen cephalosporins?

A

Cefazolin (ancef)
cephalexin

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12
Q

2nd gen cephalosporins?

A

cefaclor
cefoxitin
cefotetan

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13
Q

3rd gen cephalosporins?

A

ceftriaxone
cefotaxime
ceftazadime

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14
Q

4th gen cephalosporins?

A

cefapime

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15
Q

5th gen cephalosporins?

A

ceftaroline ($)

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16
Q

what are the carbapenems?

A

(DIME)
Doripenem
Imipenem
Meropenem
Ertapenem

17
Q

Whats the monobactam?

A

aztreonam (for penicillin allergy)

18
Q

Which abx disrupts the cell membrane?

A

Daptomycin or Cubicin (makes efflux pumps)
Polymyxins (nuke) so used topically

19
Q

Folic acid inhibitors?

A

(sulfonamides) sulfamethoxazole (1st step)
trimethoprim (2nd step)

20
Q

what is sulfamethoxazole + trimethoprim?

A

Bactrim

21
Q

What abx disrupts DNA integrity and how?

A

metronidazole
makes ROS’s

22
Q

What targets mRNA polymerase?

A

Rifampin (never alone for TB)

23
Q

What targets DNA gyrase and is found in phagocytic cells?

A

Fluoroquinolones

24
Q

1st gen fluoroquinolones?

A

Ciprofloxacin
Levofloxacin
norfloxacin
gatifloxacin

25
Q

what is the quinolone and what does it target?

A

Nalidixic acid
targets DNA gyrase like the other fluoroquinolones

26
Q

What targets the 50s subunit?

A
  • Macrolides (ACE)
    Azithromycin, Clarithromycin, Erythromycin
  • Lincosamides (Clindamycin)
  • Streptogramins
    (Quinopristin+Dalfopristin=Synercid)
  • Chloramphenicol (eye drops)
  • Oxazolidinones (linezolid) or zyvox
27
Q

What targets the 30s subunit?

A

tetracyclines
doxycycline, tetracycline, minocycline

glycylcycline (overcomes efflux pump resistance)
tigecycline

-Aminoglycosides (GNATS)
Streptomycin, Kanamycin, Neomycin, Amikacin, Gentamicin, Tobramycin

Disease N Disease (2 decks)

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