Antibiotics - Antibiotic Man 2020 Flashcards

1
Q

Meningitis

A

Ceftriaxone IV 2g bd + Dexamethasone IV 10 mg

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2
Q

Epiglottitis/Supraglottitis

A

Cefriaxone IV 2g od

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3
Q

Tonsillitis

A

1st = Penicillin

IF PA = Clarithromycin 500 mg

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4
Q

Sinusitis

A

1st Penicillin V 500 mg

2nd = Doxycycline 200 mg

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5
Q

Acute Otitis Media

A
1st = Amoxicillin
2nd = Clarithromycin

Abx IF: doesn’t settle w/in 72 Hrs OR systemic features present w/ perfusion

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6
Q

Community Acquired Pneumonia - Mild/Mod

A

Amoxicillin

IF PA = Doxycycline PO 200 mg on day.
IF NBM = IV Clarithromycin

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7
Q

Community Acquired Pneumonia - Severe

A

Co-Amoxiclav IV 1.2g + Doxycycline

IF PA = IV Levofloxacin 500 mg bd

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8
Q

Community Acquired Pneumonia - ICU/HDU or NBM

A

Co-Amoxiclav IV 1.2g + Clarithromycin 500 mg

IF PA = IV Levofloxacin 500 mg bd

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9
Q

Hospital Acquired Pneumonia - non-severe

A

PO Amoxicillin + Metronidazole

IF PA = Doxycycline 100 mg bd x 5 days

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10
Q

Hospital Acquired Pneumonia - Severe

A

IV Amoxicillin + Metronidazole + Gentamicin

IF PA = Amoxicillin  Doxycycline OR IV Clarithromycin

Step down: PO Co-Trimoxazole

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11
Q

Aspiration Pneumonia: Non-severe

A

PO Amoxicillin + Metronidazole

IF PA: A –> Doxycycline

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12
Q

Aspiration Pneumonia: Severe

A

IV Amoxicillin + Metronidazole + Gentamicin

IF PA = Amoxicillin  Doxycycline OR IV Clarithromycin

Step down: PO Amoxicillin + metronidazole

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13
Q

Acute Exacerbation of COPD

A

1st line = Amoxicillin 500 mg
2nd line = Doxycyline 500 mg

Only start Abx IF ↑ sputum purulence. NO sputum purulence = no Abx unless CXR consolidation

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14
Q

Acute Cough/Acute bronchitis

A

1st line = Amoxicillin 500 mg

2nd line = Doxycyline 500 mg

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15
Q

Endocarditis - Native valve/recent dental work

A

Amoxicillin IV 2g + Gentamicin 1mg/kg

Viridans Streptococci

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16
Q

Endocarditis - Native valve/severe sepsis/IV drug user

A

Flucloxacillin IV 2g

Staphylococcus aureus

17
Q

Endocarditis = Prosthetic valve or suspected MRSA

A

Vancomycin IV + Gentamicin IV

Staphylococcus epidermidis

Once Vancomycin therapeutic range is met = change to Rifampicin PO

18
Q

Gut-bound bacterial endocarditis

A

Amoxicillin

Enterococcus faecalis + Streptococcus bouis

IF PA = Vancomycin + Gentamicin

19
Q

Clostridium difficile: Non-severe

A

Metronidazole PO 400 mg

20
Q

Clostridium difficile: Severe

A

Vancomycin +/- Metronidazole

Must give vancomycin orally!!

21
Q

Peritonitis/Biliary tract/Intra-abdominal infection

A

IV Amoxicillin + Metronidazole + Gentamicin

IF PA= Vancomycin

Step down: PO Co-Trimoxazole + Metronidazole

22
Q

Proven Spontaneous Bacterial Peritonitis: Mild

A

Co-Trimoxazole PO

23
Q

Proven Spontaneous Bacterial Peritonitis: Severe

A

Piperacillin/Tazobactam IV

Step down: Co-Trimoxazole

24
Q

Complicated UTI/Pyelonephritis/ Urosepsis

A

IV Amoxicillin + Gentamicin

IF PA = IV Co-Trimoxazole + Gent.
Step-Down: PO Co-Trimoxazole

25
Q

Uncomplicated Female UTI

A

Nitrofurantoin 100 mg
OR Trimethoprim 200 mg

3 Days

26
Q

Uncatherised Male UTI

A

Nitrofurantoin 100 mg
OR Trimethoprim 200 mg

7 Days

27
Q

Cellulitis

A

Flucloxacillin 1g qds

IF PA = Doxycycline 100 mg PO

28
Q

Open Fracture Prophylaxis

A

IV Co-Amoxiclav 1.2g tds

Start within 3 Hours for max 72 Hours

29
Q

Diabetic Foot Infection: Mild

A

Flucloxacillin 1g

IF PA = Doxycycline

30
Q

Diabetic Foot Infection: Moderate

A

Flucloxacillin 1g + Metronidazole 400 mg

IF PA = Doxycycline

31
Q

Acute Septic Arthritis/Osteomyelitis

A

IV Flucloxacillin 2g qds

32
Q

Severe Systemic Infection of Unknown Source

A

IV Amoxicillin + Metronidazole + Gentamicin

IF PA = Amoxicillin –> Vancomycin

33
Q

Athlete’s Foot

A

Topical 1% terbinafine - 7 days

34
Q

Dermatophyte Nail Infection

A

Terbinafine 250 mg

Fingers = 6 weeks
Toes = 12 weeks
35
Q

Dog/Cat bite

A

1st = Co-Amoxiclav 625 mg

2nd = Metronidazole 400 mg + Doxycycline 100 mg

36
Q

Human Bite

A

1st = Co-Amoxiclav 625 mg

2nd = Metronidazole 400 mg + Clarithromycin 600 mg

37
Q

Impetigo

A

Localised lesions = Topical Fusidic acid

Otherwise: 1st line = Flucloxacillin 500 mg
2nd = Clarithromycin