Antibiotics and bacteria Flashcards

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1
Q

ceftriaxone is a what
covers what
why is it used in meningitis

A

cephalosporin
gram pos and gram neg
easy twice daily dosing and good concentration in CNS compared to penicillin

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2
Q

listeria is resistant to what

A

cephalosporin

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3
Q

why is ceftriaxone given i epiglottis and not amox

A

greater tissue levels and whilst 75% of HI is sensitive to amox 25% parents - usually beta lactase produgin

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4
Q

group A-G sensitive to what

A

penicillin

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5
Q

why in sinutisit is amox given when pneumococcal is also sensitive to penicillin

A

amox has better oral absorption

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6
Q

what is used for atypical cover in CAP

A

clarithromycin and doxy

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7
Q

what does levofloxacin have cover against

A

MSSA, HI, pneumococci, colifroms and leigonella

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8
Q

when should antibiotics be given in acute exacerbation of COPD

A

purulent sputum, signs of pneumonia, CXR shows consolidation

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9
Q

when should treatment be given in acute bronchitis

A

if frail and elderly

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10
Q

in native valve subacute ix and treatment when

A

3 sets of blood cultures 6 hours apart

give ABs after 6 hours if patient stable

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11
Q

in native valve acute ix and treatment

A

2 sets of blood cultures and ABs immediately - within 1h

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12
Q

MRSA is resistant to what

A

flucloxacillin and coag neg staph

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13
Q

metro

A

anaerobes

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14
Q

gentamicin

A

coliforms

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15
Q

extended spectrum beta lactase resistant to what

sensitiv to what

A

all penicillins and cephalosporins

sensitive to temocillin and meropenam

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16
Q

why is nitro only given in lower uTIs

A

no kidney penetration

high concentrations in urine

17
Q

alpha haemolysis

A

partial haemolysis - green discolouration around agar

18
Q

beta haemolytic strep

A

strep pyrogens

full haemolysis - total clearance

19
Q

enterococci faecalis

faecum

A

no haemolsyis

faecum - hard to treat other one sens to amox

20
Q

C Diff gram pos bacilli anaerobic toxin A toxin B

A

A enterotoxin

B cytotoxin