Antibiotics

Question 1

Abx Prophylaxis for ERCP - no penicillin allergy

Answer 1

PO ciprofloxacin 500 mg - 60 to 90 minutes prior to procedure or 400 mg IV over 60 minutes beginning within 120 minutes prior to procedure

AND/OR
Amoxicillin-clavulanate 1750 mg PO within 60 minutes prior to procedure.

AND/OR Ampicillin 2 grams IV + gentamicin 5 mg/kg within 60 minutes before procedure.

Question 2

Abx Prophylaxis for ERCP - Penicillin allergy

Answer 2

vancomycin + Genta
vancomycin 15 mg/kg (maximum 2 g) IV infused over 60 to 90 minutes beginning within 120 minutes before procedure plus gentamicin¥ 5 mg/kg IV (pediatric 2.5 mg/kg) within 60 minutes before procedure.

Question 3

What type of ABx is Ciprofloxacin?

Answer 3

Fluoroquinolone

Question 4

fluoroquinolone MOA?

Answer 4

Directly inhibit bacterial DNA synthesis

Question 5

Fluoroquinolones SPECTRUM OF ACTIVITY?

Answer 5

Broad-spectrum - aerobic, enteric gram-negative bacilli and many common respiratory pathogens.

Question 6

which fluoroquinolone has the greates activity against aerobic gram negative bacilli?

Answer 6

ciprofloxacin

Question 7

which fluoroquinolone has the greates activity against gram-positive organisms?

Answer 7

levofloxacin and moxifloxacin

Question 8

Against which organisms does ciprofloxacin has high potency?

Answer 8

Aerobic, Enteric gram-negative bacilli (eg, Enterobacteriaceae, including Escherichia coli, Klebsiella spp, Proteus spp).
In addition, ciprofloxacin is also active against Pseudomonas spp

Question 9

Iv abc for cystitis?

Answer 9

Ciproflixacin 400mg 2/day for 5-7days