Antibiotics Flashcards
Memorize the key concepts of antibiotics when prescribing. Learning specific antibiotic classes, bacteria and identify which antibiotics or which bacterial infections.
List Gram + Bacteria
- ) Staph
- ) Strept
- ) Enterococcus
- ) Listeria
- ) Propionbacterium
- ) Corynebacterium (diptheria)
- ) Clostridium
- ) Tetanus, Botulism
- ) Bacillus anthracis
List Gram Negative Bacteria
Just about Everything Else
- ) Neisseria gonorrhoeae
- ) Neisseria menngitidis
- ) E Coli, Shigella, Campylobactor
- ) Salmonella, Pasturella
- ) Rickettsia, Borrelia
- ) Proteus, Pseudomonas, Legionella
List atypical Gram Negative Bacteria
Mycoplasma
H.Flu
M.Cat
Legionella
List Staphylococcus Gram Positive Bacteria
Staphylococcus aureus (skin) MSSA (Staphylococcus aureus) (skin) MRSA (staphylococcus aureus (skin) Staph saprophyticus (UTI, Vagina) Staph epidermis (skin)
What are the Gram Positive Streptococcus Bacteria
Strept pyogens (throat) Strept pneumoniae (lungs) Strept viridans (dental abscess, endocarditis) Strept agalactiae (Group B Strept)
What are the 2 Concepts of “Empiric Treatment”
- ) Consider the difference between Gram Positive and Gram Negative Bacteria
- ) Consider Beta Lactam Ring
Define the meaning of “Beta Lactam”
- ) An antibiotic with a beta-lactam ring
2. ) All PCN and Cephalosporins
When prescribing PCN or Cephalosporin what 2 Points are ALWAYS considered?
- ) Hx of Allergic reactions
2. ) Beta Lactamase antibiotic
Can patients with allergy to PCN take a Cephalosporin
- ) Consider patient allergy to PCN
- ) Both PCN and Cephalo share beta lactamase but allergy to PCN is an allergy to the “pink pentagon” component of the PCN molecule. This differs from the “blue hexagon” of the cephalo molecule
- ) 90-98% of PCN allergy pts are allergic to the “pink pentagon” AND can safely take cephalosporin
- ) 2-10% of PCN allergy patients are ALSO allergic to the “blue hexagon” on the cephalo molecule therefore are allergic to both
What are “Amelie’s Rules” for Prescribing a Cephalosporin
- ) NEVER give cephalo if PCN allergy was anaphylaxis
- ) Don’t give cephalo if PCN reaction was hives
- ) GIVE cephalo is PCN reaction was morbilliform rash
This rash is…
Maculopapular or macular with fixed lesions and expands over several days
Itches
Prevalent most in kids
Most common with aminopenicillins (amox & ampicillin)
Morbiilliform Rash
This rash is usually T Cell mediated
This rash may arise after concurrent viral infections
Unknown mechanism of occurence
Morbilliform Rash
This is an enzyme in which bacteria know how to produce
Beta-Lactamase
What does Beta-Lactamase Do?
Beta Lactamase destroys the beta-lactam ring of the antibiotic
What Bacteria are PCNs USED for..
Gram + NOT Staphylococcus Strep Groups: A,B,C,G Enterococcus Strept pneumonaie Drug Resistant Strep Pneumo (DRSP) Botulism (wound, not food)