Antibiotics Flashcards

1
Q

Antibiotics for mild/moderate C. difficile

A

Metronidazole P.O. 10 days

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2
Q

Antibiotics for severe C. difficile

A

Vancomycin P.O. 10 days

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3
Q

Antibiotics for Non responders in C. difficile infection

A

Vancomycin + IV metronidazole

Fidaxomicin

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4
Q

Antibiotics for mild/moderate peritonitis/biliary sepsis

A

Co-amoxiclav IV

PO Once stable for 5 days

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5
Q

Antibiotics for mild/moderate peritonitis/biliary sepsis for penicillin allergic

A

Meropenem IV

Metronidazole + ciprofloxacin 5 days once stable

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6
Q

Antibiotics for severe/ITU peritonitis/biliary sepsis

A

Piperacillin/Tazobactam IV

Meropenem IV

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7
Q

Empirical Antibiotics for septic arthritis

A
Flucloxacillin IV
Vancomycin IV (PA)
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8
Q

Antibiotic management for septic arthritis with staph aureus

A

Flucloxacillin IV for 5 days
PO for 6 weeks

Vancomycin IV for 5 days
Doxycycline P.O. for 6 weeks

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9
Q

Antibiotics for streptococci septic arthritis

A

Benzylpenicillin IV 5 days
Amoxicillin P.O. 6 weeks

Vancomycin IV 5 days
Doxycycline P.O. 6 weeks

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10
Q

Infected joint replacement antibiotics

A

Empirical
Flucloxacillin IV
Vancomycin IV

Org-specific:
Same as septic arthritis

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11
Q

Antibiotics for mild CAP

A

Amoxicillin P.O. 5 days

Doxycycline P.O. 5 days

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12
Q

Antibiotics for moderate CAP

A

Amoxicillin + doxycycline P.O. 5 days

Doxycycline P.O. 5 days

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13
Q

Antibiotics for severe CAP

A

Coamoxiclav IV + doxycycline P.O. 5 days

Meropenem IV + doxycycline P.O. 5 days

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14
Q

Antibiotics for mild/moderate HAP

A

Co amoxiclav PO 5 days

Doxycycline P.O. 5 days

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15
Q

Antibiotics for severe HAP

A

Coamoxiclav IV 5 days

Meropenem IV 5 days

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16
Q

Antibiotics for mild/moderate aspiration pneumonia

A

Co amoxiclav P.O. 5 days

Ciprofloxacin + metronidazole P.O. 5 days

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17
Q

Antibiotics for severe aspiration pneumonia

A

Coamoxiclav IV 5 days

Meropenem IV 5 days

18
Q

Antibiotics for ventilator associated pneumonia

A

Piperacillin + tazobactam IV 5 days

Meropenem IV 5 days

19
Q

COPD infective exacerbation antibiotics

A

Co amoxiclav P.O. 5 days

Doxycycline P.O. 5 days

20
Q

Antibiotics for uncomplicated UTI

A

Trimethoprim P.O. 3 days

2nd line: nitrofurantoin

21
Q

Antibiotics for complicated UTI

A

Trimethoprim P.O. 5 days
Or nitrofurantoin
2nd line: co amoxiclav P.O. 5 days

22
Q

Complicated uti with sepsis

A

Coamoxiclav IV 5 days

Meropenem IV 5 days

23
Q

Pyelonephritis antibiotics

A

Co amoxiclav P.O. 14 days

Ciprofloxacin P.O. 7 days

24
Q

Mild cellulitis/erysipelas

A

Flucloxacillin P.O. 7 days

Doxycycline P.O. 7 days

25
Q

Severe cellulitis

A

Flucloxacillin IV 7 days

Vancomycin IV 7 days

26
Q

Meningitis empirical antibiotics

A

ceftriaxone IV

>55: ceftriaxone + amoxicillin IV

27
Q

Meningitis with no organism on culture

A

Ceftriaxone IV 10 days

28
Q

Meningitis with N meningitidis

A

Ceftriaxone Iv 5 days

29
Q

Meningitis with strep pneumoniae

A

Ceftriaxone IV 10 days

30
Q

Meningitis with h influenzae

A

Ceftriaxone IV 10 days

31
Q

Antibiotics for mild diabetic foot infection

A

FlucloxCillin P.O. 14 days

Doxycycline P.O. 14 days

32
Q

Moderate diabetic foot infection

A

Flucloxacillin + ciprofloxacin + metronidazole P.O. 14 days

Doxycycline + ciprofloxacin + metronidazole P.O. 14 days

33
Q

Severe diabetic foot infection

A

Piperacillin + tazobactam + vancomycin IV 14 days

Meropenem + vancomycin IV 14 days

34
Q

Empirical antibiotic treatment for native valve infective endocarditis

A

Ampicillin
Flucloxacillin
Gentamicin

35
Q

Empirical antibiotics for prosthetic valve infective valve endocarditis

A

Vancomycin
Gentamicin
Rifampicin

36
Q

Staph infective endocarditis for native valve

A

Flucloxacillin IV 4-6 weeks

37
Q

Staph infective endocarditis for prosthetic valve

A

Flucloxacillin + rifampicin + gentamicin IV 6 weeks

38
Q

Streptococci infective endocarditis for native valve

A

Benzylpenicillin IV 4-6 weeks

39
Q

Signs of red flag sepsis

A
RR >25
BP <90 
Anuria/oliguria 
Respond to pain/unresponsive 
Non blanching rash
Cyanotic 
Mottled
Neutropenic
Chemotherapy
40
Q

Definition of red flag sepsis

A

EWS >/= 3
Clinical suspicion of infection
One of Red flag signs

41
Q

Management of non red flag sepsis

A

Source specific abx

42
Q

Management of red flag sepsis

A
Sepsis 6 bundle in 1 hour: 
High flow oxygen 
Blood culture 
IV Antibiotics: IV meropenem 1g stat 
Fluid challenge
Lactate 
Urine output