Antibiotics Flashcards
What is empiracal therapy?
An educated guess based on clinical symptoms. Used for more severe infections.
What is guided therapy
Identifying the cause of the infection and select agent based on sensitive testing. Used for mild infections
What is prophylactic therapy
The prevention of an infection before it even starts
Who is prophylactic therapy directed at?
People who are immunocompromised ie. have HIV or people who have been exposed to surgery/injury
What are the 3 main principles of antibiotic resistance
- Mutation of target site
- Inactivating enzymes
- Limit access
What are the 2 main classes of antibiotics?
Bactericidal and bacteriostatic
Describe bacteriocidal antibiotics
Sterilise site by directly killing bacteria
Give an example of a bactericidal antibiotic
penicillin
Describe bacteriostatic antibiotics
Suppress bacteria growth but does not completley sterilise the site
Give an example of a bacteriostatic antibiotic
clarithromycin
Name 2 classes of antibiotic
cell wall agents, protein synthesis inhibitors and
Give an example of a cell wall agent
penicillins
Give an exmaple of protein synthesis inibitors
macrolides