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PM2A infections > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

Penicillins

A

Peptidoglycan synthesis, inhibit cell wall

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2
Q

Cephalosporins

A

Peptidoglycan synthesis, inhibit cell wall

Cefalexin

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3
Q

Carbapenems

A

Peptidoglycan synthesis, inhibit cell wall,
last resort, Broad spec, both G-ve and G+ve
Imipenem

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4
Q

Tetracyclines

A

Inhibit 30S protein synthesis -static
Broad spec
Chlamydia, Lymes
2nd line in allergic patients

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5
Q

Chloramphenicol

A

Inhibit 50S protein synthesis -static

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6
Q

Aminoglycosides

A

Inhibit 30S protein synthesis
Aerobic G-ve, mainly enteric
Gentamicin, streptomycin

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7
Q

Macrolides

A

Inhibit 50S protein synthesis
Same spec as penicillins
Erythromycin, Clarithromycin

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8
Q

Lincosamides

A

Inhibit protein synthesis
Clindamycin
G+ve cocci

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9
Q

Quinolones/fluoroquinolones

A

DNA Gyrase/topsomirase
ciprofloxacin (anthrax)
norfloxacin (UTI)
Nalidixic acid (UTI)

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10
Q

Glycopeptides

A

Cell wall synthesis

Vancomycin -cidal

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11
Q

Polymixins

A

Interfere with cell membrane -cidal

Colistin

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12
Q

Isoniazid

A

Mycolic acid synthesis

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13
Q

Trimethoprim

A

Inhibit folate synthesis, folate antagonist

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14
Q

Sulfonamides

A

Inhibit folate synthesis, compete with PABA (folate precursor)

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PM2A infections (4 decks)

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