Antibiotics Flashcards
1
Q
Glycopeptides and beta lactams
A
Disrupt cell wall synthesis
Inhibits cross linking of peptidoglycan cell walls
2
Q
Tetracyclines
A
Disrupt protein synthesis
Lock the tRNA to the septal site of mRNA
3
Q
Aminoglycosides
A
Disrupt protein synthesis
Prevents mRNA translation on the 30s subunits
4
Q
Macrolides
A
Disrupt protein synthesis
Bind to the 50s subunit
5
Q
Quinolones
A
Disrupt nucleic acid synthesis
Inhibits bacterial DNA gyrase, which inhibits coiling
6
Q
Polymixins
A
Disrupt cell membrane function
7
Q
Sulphonamide and trimethoprim
A
Inhibits dihydrofolate reductase and inhibits folic acid synthesis
8
Q
Metronidazole
A
Affects bacterial DNA
Forms toxic metabolites which inhibits nucleic acid synthesis
