Antibiotics Flashcards
Amoxacillin/clavulonic acid
augmentin
piperacillin/tazobactam
zosyn
ampiciliin/sulbactam
unasyn
zyvox
linezolid
Augmentin indication
PO abx for outpatient therapy for polymicrobial infections
Augmentin spectrum of activity
staph, strep, enterococci, gram negative, anaerobes
Renal dose for zosyn
2.25 g IV q6hr
penicillins that cover pseudo
piperacillin, ticarcillin, carbenicillin, mezlocillin, azlocillin
How does probenecid interact with penecilins
it increases duration of serum levels of PCN and cephalosporins
how does the coverage of cephalosporins change as you increase in generations
more gram negative coverage
which cephalosporin covers pseudomonas
ceftazadime
what should the vancomycin peak and trough be
peak 15-30mg/ml
trough
caused by a anaphylactoid reaction where histamine is released by mast cells, leads to erythema and pruritis to the head, neck, and upper torso
red man syndrome-too much vanco too quickly
treatment for red man syndrome?
antihistamine like benadryl
side effects of vancomycin
ototoxicity and nephrotoxicity
when should you use oral vancomycin and what is the dosage
used to treat pseudomembranous colitis, 125mg q6hr
Spectrum of coverage for bactrim
gram positives including MRSA, and gram negatives
what allergy should be avoided when RX bactrim
sulfa allergy
side effects of bactrim
hemolytic anemia, hypersensitivity
indication for invanz
treatment of moderate to severe diabetic foot infections
major side effect of zyvox
thrombocytopenia
spectrum for aztreonam
gram negative aerobes and pseudo
aminoglycoside spectrum of activity
gram negative aerobes
side effect of clinda and where is it metabolized
side effect is pseudomembranous colitis and is metabolized in the liever
