Antibiotics Flashcards

1
Q

Amoxacillin/clavulonic acid

A

augmentin

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2
Q

piperacillin/tazobactam

A

zosyn

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3
Q

ampiciliin/sulbactam

A

unasyn

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4
Q

zyvox

A

linezolid

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5
Q

Augmentin indication

A

PO abx for outpatient therapy for polymicrobial infections

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6
Q

Augmentin spectrum of activity

A

staph, strep, enterococci, gram negative, anaerobes

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7
Q

Renal dose for zosyn

A

2.25 g IV q6hr

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8
Q

penicillins that cover pseudo

A

piperacillin, ticarcillin, carbenicillin, mezlocillin, azlocillin

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9
Q

How does probenecid interact with penecilins

A

it increases duration of serum levels of PCN and cephalosporins

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10
Q

how does the coverage of cephalosporins change as you increase in generations

A

more gram negative coverage

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11
Q

which cephalosporin covers pseudomonas

A

ceftazadime

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12
Q

what should the vancomycin peak and trough be

A

peak 15-30mg/ml

trough

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13
Q

caused by a anaphylactoid reaction where histamine is released by mast cells, leads to erythema and pruritis to the head, neck, and upper torso

A

red man syndrome-too much vanco too quickly

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14
Q

treatment for red man syndrome?

A

antihistamine like benadryl

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15
Q

side effects of vancomycin

A

ototoxicity and nephrotoxicity

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16
Q

when should you use oral vancomycin and what is the dosage

A

used to treat pseudomembranous colitis, 125mg q6hr

17
Q

Spectrum of coverage for bactrim

A

gram positives including MRSA, and gram negatives

18
Q

what allergy should be avoided when RX bactrim

A

sulfa allergy

19
Q

side effects of bactrim

A

hemolytic anemia, hypersensitivity

20
Q

indication for invanz

A

treatment of moderate to severe diabetic foot infections

21
Q

major side effect of zyvox

A

thrombocytopenia

22
Q

spectrum for aztreonam

A

gram negative aerobes and pseudo

23
Q

aminoglycoside spectrum of activity

A

gram negative aerobes

24
Q

side effect of clinda and where is it metabolized

A

side effect is pseudomembranous colitis and is metabolized in the liever

25
Q

dosage for flagyl (metronidazole)

A

500mg TID

26
Q

What abx cover MRSA

A

linezolid, minocycline, cipro/rifampin, bactrim/rifampin, vancomycin, synercid, tigcyclin, bactroban

27
Q

treatment for VRE

A

linezolid or dalfopristin/quinupristin

28
Q

drugs that cover pseudo

A

aztreonam, aminoglycosides, cipro, ceftazidime, cefepime, timentin, zosyn

29
Q

should the abx used in PMMA beads be heat labile or not.

A

Must not be heat labile because curing of PMMA is exothermic.

30
Q

which drugs are used for PMMA beads

A

vancomycin, gentamycin, tobramycin, cefazolin