Antibiotics

Question 1

GAS

Answer 1

Penicillin or Amoxicillin (if allergic then azithro)

Question 2

Strep agalactiae

Answer 2

Penicillin or amoxi for non sepsis amd enigitis

Neonatal meningitis - cefotaxime + ampicillin

Question 3

Strep viridans

Answer 3

Penicillin

Question 4

Strep pneumoniae

Answer 4

M (adult) - ceftriaxone/cefotaxime + vancomycin (+ampi if pregnant)
O - Ampicillin/ Amoxicillin
P - Amoxicillin (mild)
Levofloxocin (mild or severe)
Ceftriaxone+Azithromycin/Doxy (severe)
S/S - Ampicillin/ Amoxicillin

Question 5

Enterococcus

Answer 5

Ampicillin if susceptible, then Vanco if ampi resistant, then linezolid or dapto if VRE

Question 6

staph sapro

Answer 6

TMP/SMZ

Question 7

staph epid

Answer 7

vancomycin and remove/replace device; if resistant then linezolid or daptomycin

Question 8

staph aureus

Answer 8

1st line - nafcillin - MSSA or cefazolin (IV)/cephalexin (oral)
MRSA - vancomycin (mostly IV) or daptomycin or linezolid, 2nd line - ceftaroline, TMP/SMZ, doxycycline, clindamycin

Question 9

actinomyces

Answer 9

penicillin

Question 10

nocardia

Answer 10

tmp/smz

Question 11

c. diphtherium

Answer 11

DtAp child or tdap booster vaccine or anti toxin and do not scrape membrane

Question 12

listeria

Answer 12

ampicillin

Question 13

bacillus cereus

Answer 13

tetracycline or levofloxacin

Question 14

c. diff

Answer 14

oral vanco - colitis, metronidazole (oral or IV)

Question 15

c. perfringes

Answer 15

penicillin

Question 16

c.botulinism

Answer 16

anti-toxin

Question 17

c. tetani

Answer 17

anti-toxin, tdap/dtap vaccine

Question 18

Myco fortuitum

Answer 18

clarithromycin + amikacin (if necessay) and surgical debridement

Question 19

myco tuberculosis

Answer 19

RIPE for 2 months and RI for 4 months

Question 20

Treponema pallidum

Answer 20

penicillin always (for early stages doxy as alternative if allergic)

Question 21

leptospira (zoonotic)

Answer 21

penicillin or doxy

Question 22

borrelia burgdoferi (tick borne)

Answer 22

doxycycline for stage 1, ceftriaxone stage 2 and 3. for kids and pregnant women amoxicillin and cefotaxime

Question 23

rickettsia + anaplasma + erlichia

Answer 23

doxy for all. no exceptions for rickettsii but can do amoxi for kids and pregnant women for the other two

Question 24

coxiella, brucella, bartonella, franciscella

Answer 24

doxy or you don’t have to know

Question 25

mycoplasma and chlamydophila pneumo

Answer 25

doxy or azithromycin or levofloxacin

Question 26

chlamydia trachomatis

Answer 26

azithromycin (1 day) + doxy or levo (7days) + ceftriaxone for gonorrhea co-infection

Question 27

neisseria meningitidis

Answer 27

meningitis - ceftriaxone/cefotaxime | rifampin for close contacts; ACYW-135 vaccine for asplenics and older kids

Question 28

neisseria gonrrhea

Answer 28

ceftriaxone + (azithro+doxy/levo) for chlamydia co-infection

Question 29

moraxella

Answer 29

ceftriaxone

Question 30

H. influenzae

Answer 30

cefriaxone + vanco, rifampin for close contacts, HIB vaccine for infants and asplenics

Question 31

H. ducreyi

Answer 31

ceftriaxone, azithromycin, or ciprofloxacin

Question 32

bordetella pertussis

Answer 32

azithromycin to prevent spread - is supportive. tdap/dtap

Question 33

legionella

Answer 33

azithromycin, levo, doxy

Question 34

proteus

Answer 34

tmp/smz

Question 35

citrobacter

Answer 35

SPICE org - carbapenem

Question 36

enterobacter

Answer 36

SPICE org - carbapenem

Question 37

campylobacter and vibio

Answer 37

not treated but if necessary (immunocomp) azithromycin | anti toxin available for vibrio

Question 38

helicobacter

Answer 38

triple therapy: proton pump + clarithromycin + amoxi/metronidazole

Question 39

klebsiella

Answer 39

Extended spectrum such as cefepime, cefuroxime, cefoxitin, piperacillin + B lactam inhibitor, or aztreonam if ESBL than carbapenems if kpc and last resort polymixins

Question 40

bacteroides

Answer 40

piperacillin/tazobactam

Question 41

yersinia

Answer 41

not needed, azithro if necessary

Question 42

shigella

Answer 42

not needed in healthy but to prevent spread | ceftriaxone, cipro, or azithromycin

Question 43

salmonella

Answer 43

typhi - ceftriaxone non typhi - not needed

Question 44

E.coli

Answer 44

UTI - lower = TMP/SMZ; upper = ceftriaxone or cipro; nosocomials = carbapenems; neonatal meninigits = cefotaxime/ampicillin

Question 45

pseudomonas

Answer 45

Extended spectrum such as cefepime, cefuroxime, cefoxitin, piperacillin + tazobactam, aztreonam, cipro, amikacin, imipenem-cilastin and last resort polymixins