Antibiotics Flashcards
Antibiotics Can Protect The Queens Men Servants & Guards
- Aminoglycoside
- Cephalosporin
- Penicillin
- Tetracycline
- Quinolone / Fluoroquinolones
- Macrolide
- Sulphonamide
- Glycopeptides
mechanism of action
Aminoglycosides
streptomicin, gentamicin
Inhibit 30S
Inhibits protein synthesis
mechanism of action
Cephalosporins
Cefazolin
Inhibit cell wall synthesis
mechanism of action
Penicillin
Penicillin, methicillin
Inhibit cell wall syntehsis
mechanism of action
Tetracyclines
Tetra and Doxycycline
Inhibits 30s Protein synthesis
mechanism of action
Quinolones
Ciproflaxin
Inhibit DNA replication at topoisomerase II and IV
mechanism of action
Macrolides
Erythromycin
Inhibit protein synthesis at 50s
mechanism of action
Sulphonamides
Sulphamethexzole
Inhibits folate synthesis
mechanism of action
Glycopeptides
Vancomycin
Inhibits cell wall synthesis
Tetracyclines may cause
- discolouration of teeth
- Photosensitivity
- Intracranialhypertension
Aminoglycosides may cause
Ototoxicity
Nephrotoxicity
Chloramphenicol may cause
Aplastic anaemia
Clindamycin may cause
Common cause of C. difficile diarrhoea
Macrolides may cause
- Nausea (especially erythromycin)
- P450 inhibitor
- prolonged QT interval
Commonly used for patients who are allergic to penicillin
