Antibiotics Flashcards
Which pathogens are covered by Pen V, K and Pen G?
-Strep thorat
-Syphillis
Which drugs only cover MSSA?
Nafcillin (IV)
Dicloxacillin (oral)
Oxacillin
When switching from Penicillins to Amoxicllin or Ampicillin which organs are covered in addition to Staph and Strep?
Enterococcus
freindly nega (pan-sensitive gram neg)
E. coli, Klebsiellla, …
When using Augmentin or Amp/Sulb which bugs are covered in addition to those of Amoxicillin and Ampicillin?
-GI tract anaerobes
-doc bites, cat bites
Breathing, Belly, Bites
Which drug is a ß-lactam with a ß-lactamase inhibitor that also covers Pseudomonas?
Pip/tazo
When moving to early to later Cephalosporin gens, how does the coverage change?
more gram negatives as we go further down the gen, sometimes we give up gram pos coverage
Which organism that is covered by ß-lactams is not covered by Cephaosporin?
Enterococcus
exception: Cefepime
Which Cephalosporin covers anaerobes?
Cefazolin?
Which Cephalosporin covers anaerobes (with flagyl)?
Cefepime + Flagyl??? covers anerobes
like Zosyn
-
-but no Enterococcus coverage
Coverage of Meropenem
enteroccous
-staph
-strep
gram negatives
-pseuodomonas
-anaerobics?
Coverage of Ert(ape)nem
ape
A
P
E
When would we use Ertapenem?
ESPLs
When would Aztreonem be a choice?
NAPLEX
true PNC allergy
it only has gram neg. coverage???
MOA of Fluroquniolones
DNA Gyrase inhibition
DNA unwinding?
What are the atypicals? Which part of the body do they typically infect?
- Mycoplasme
- Legionella
infects the respiratory tract -> Pneumonia, URI, otitis media
What needs to be checked before starting Daptomycin?
check CPK before starting
for rhabdomyolysis
Main side effect of Linezolid
thrombocytopenia after 2 weeks
-> so can only use for 2 weeks
Coverage of the FQ
gram-postive covaerge:
-Moxifloxicin (it also has
gram-negative:
-Cipro
some of both:
Levofloxacicin
.. doesnt cover what?
Psueodomaona and UTI
Aminoglycosides cover only gram-_____
negatives including Pseudomonas
