Antibiotics Flashcards
MOA of vancomycin?
Cell wall inhibitor
Inhibits Peptidoglycan synthesis
MOA of fosfomycin ?
Cell wall synthesis inhibitor
Inhibits peptidoglycan synthesis
Which class of ABs inhibit the cell wall synthesis? (5)
1) peptidoglycan inhibitors (vancomycin - fosfomycin)
2) penicillins ( end in -cillin)
3) cephalosporins
4)carbapenems
5)monobactams
Which ABs inhibit the cross linking of the peptidoglycans ?
Beta lactams
What are the 4 groups of beta lactams ?
1) monobactam
2) cephalosporins
3) cephamycin
4) carbapenem
What are the natural penicillins ? (2)
1)penG (IV - IM)
2)penV (PO)
What are the anti staphylococcal penicillins ? (3)
1) oxacillin
2) naphicillin
3) dicloxacillin
How many generations to cephalosporins have?
5
What are the first generation cephalosporins ? (2)
1) Cefazoline
2) cefalexin
What are the second generation cephalosporins ? (3)
1) cefaclor
2) cefaxitin
3) cefotitin
What are the third generation cephalosporins? (3)
1) ceftriaxone
2) cefotaxime
3) ceftazedime
what are the fourth generation cephalosporins? (1)
Cefepime
What are the 5th generation cephalosporins?
Cefteroline
Carbapenem coverage ?
Broad spectrum
What are the 4 carbapenem drugs ? (DIME)
Doripenem
Imipenem
Meropenem
Ertrapenem
Name a monobactam antibiotic ?
Aztreonam
What are the 4 beta lactamase inhibitors ?
Clavulanate
Sulbactam
Tazobactam
Avibactam
What penicillin is mixed with clavulanate ?
Amoxicillin
What antibiotic is mixed with avibactam ?
Ceftazidime
What antibiotic is mixed with sulbactam ?
Ampicillin
What antibiotic is mixed with tazobactam?
Pepracillin
What are the antibiotics that destroy cell membrane integrity?
Daptomycin
Polymyxine
What are the antibiotics that destroy cell membrane integrity?
Daptomycin
Polymyxine
What are the antibiotics that destroy cell membrane integrity?
Daptomycin
Polymyxine