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Drugs > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

MOA of vancomycin?

A

Cell wall inhibitor
Inhibits Peptidoglycan synthesis

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2
Q

MOA of fosfomycin ?

A

Cell wall synthesis inhibitor
Inhibits peptidoglycan synthesis

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3
Q

Which class of ABs inhibit the cell wall synthesis? (5)

A

1) peptidoglycan inhibitors (vancomycin - fosfomycin)
2) penicillins ( end in -cillin)
3) cephalosporins
4)carbapenems
5)monobactams

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4
Q

Which ABs inhibit the cross linking of the peptidoglycans ?

A

Beta lactams

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5
Q

What are the 4 groups of beta lactams ?

A

1) monobactam
2) cephalosporins
3) cephamycin
4) carbapenem

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6
Q

What are the natural penicillins ? (2)

A

1)penG (IV - IM)
2)penV (PO)

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7
Q

What are the anti staphylococcal penicillins ? (3)

A

1) oxacillin
2) naphicillin
3) dicloxacillin

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8
Q

How many generations to cephalosporins have?

A

5

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9
Q

What are the first generation cephalosporins ? (2)

A

1) Cefazoline
2) cefalexin

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10
Q

What are the second generation cephalosporins ? (3)

A

1) cefaclor
2) cefaxitin
3) cefotitin

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11
Q

What are the third generation cephalosporins? (3)

A

1) ceftriaxone
2) cefotaxime
3) ceftazedime

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12
Q

what are the fourth generation cephalosporins? (1)

A

Cefepime

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13
Q

What are the 5th generation cephalosporins?

A

Cefteroline

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14
Q

Carbapenem coverage ?

A

Broad spectrum

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15
Q

What are the 4 carbapenem drugs ? (DIME)

A

Doripenem
Imipenem
Meropenem
Ertrapenem

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16
Q

Name a monobactam antibiotic ?

A

Aztreonam

17
Q

What are the 4 beta lactamase inhibitors ?

A

Clavulanate
Sulbactam
Tazobactam
Avibactam

18
Q

What penicillin is mixed with clavulanate ?

A

Amoxicillin

19
Q

What antibiotic is mixed with avibactam ?

A

Ceftazidime

20
Q

What antibiotic is mixed with sulbactam ?

A

Ampicillin

21
Q

What antibiotic is mixed with tazobactam?

A

Pepracillin

22
Q

What are the antibiotics that destroy cell membrane integrity?

A

Daptomycin
Polymyxine

23
Q

What are the antibiotics that destroy cell membrane integrity?

A

Daptomycin
Polymyxine

24
Q

What are the antibiotics that destroy cell membrane integrity?

A

Daptomycin
Polymyxine

25
Q

What are the antibiotics that inhibit the folic acid pathway?

A

Sulfamethoxazole (sulfunamides)
Trimetoprime

26
Q

What are the antibiotics that destroy DNA integrity?

A

Metronidazole
Nitropharantoin

27
Q

What antibiotic stops MRNA synthesis?

A

Rifampin

28
Q

What is the MOA of rifampin ?

A

Inhibits MRNA synthesis

29
Q

fluoroquinolone MOA ?

A

Inhibits DNA gyrase function

30
Q

What is the first generation fluoroquinolone ?

A

Cipeofloxacin

31
Q

What are the second generation fluoroquinolones ?

A

Levofloxacin
Gemifloxacin
Moxifloxacin

32
Q

What are the protein inhibitor antibiotics ?

A

1) Macrolides (azithro-erythro-clorithro)
2) Clindamycin
3) Chloramphenicol
4) Lynezolid
5) Aminoglycosides ( gentamicin- Amikacin- tobramicin)
6) tetracyclines ( doxycycline- tetracycline)

Drugs (2 decks)

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