Antibiotics

Question 1

MOA of vancomycin?

Answer 1

Cell wall inhibitor
Inhibits Peptidoglycan synthesis

Question 2

MOA of fosfomycin ?

Answer 2

Cell wall synthesis inhibitor
Inhibits peptidoglycan synthesis

Question 3

Which class of ABs inhibit the cell wall synthesis? (5)

Answer 3

1) peptidoglycan inhibitors (vancomycin - fosfomycin)
2) penicillins ( end in -cillin)
3) cephalosporins
4)carbapenems
5)monobactams

Question 4

Which ABs inhibit the cross linking of the peptidoglycans ?

Answer 4

Beta lactams

Question 5

What are the 4 groups of beta lactams ?

Answer 5

1) monobactam
2) cephalosporins
3) cephamycin
4) carbapenem

Question 6

What are the natural penicillins ? (2)

Answer 6

1)penG (IV - IM)
2)penV (PO)

Question 7

What are the anti staphylococcal penicillins ? (3)

Answer 7

1) oxacillin
2) naphicillin
3) dicloxacillin

Question 8

How many generations to cephalosporins have?

Answer 8

5

Question 9

What are the first generation cephalosporins ? (2)

Answer 9

1) Cefazoline
2) cefalexin

Question 10

What are the second generation cephalosporins ? (3)

Answer 10

1) cefaclor
2) cefaxitin
3) cefotitin

Question 11

What are the third generation cephalosporins? (3)

Answer 11

1) ceftriaxone
2) cefotaxime
3) ceftazedime

Question 12

what are the fourth generation cephalosporins? (1)

Answer 12

Cefepime

Question 13

What are the 5th generation cephalosporins?

Answer 13

Cefteroline

Question 14

Carbapenem coverage ?

Answer 14

Broad spectrum

Question 15

What are the 4 carbapenem drugs ? (DIME)

Answer 15

Doripenem
Imipenem
Meropenem
Ertrapenem

Question 16

Name a monobactam antibiotic ?

Answer 16

Aztreonam

Question 17

What are the 4 beta lactamase inhibitors ?

Answer 17

Clavulanate
Sulbactam
Tazobactam
Avibactam

Question 18

What penicillin is mixed with clavulanate ?

Answer 18

Amoxicillin

Question 19

What antibiotic is mixed with avibactam ?

Answer 19

Ceftazidime

Question 20

What antibiotic is mixed with sulbactam ?

Answer 20

Ampicillin

Question 21

What antibiotic is mixed with tazobactam?

Answer 21

Pepracillin

Question 22

What are the antibiotics that destroy cell membrane integrity?

Answer 22

Daptomycin
Polymyxine

Question 23

What are the antibiotics that destroy cell membrane integrity?

Answer 23

Daptomycin
Polymyxine

Question 24

What are the antibiotics that destroy cell membrane integrity?

Answer 24

Daptomycin
Polymyxine

Question 25

What are the antibiotics that inhibit the folic acid pathway?

Answer 25

Sulfamethoxazole (sulfunamides) Trimetoprime

Question 26

What are the antibiotics that destroy DNA integrity?

Answer 26

Metronidazole Nitropharantoin

Question 27

What antibiotic stops MRNA synthesis?

Answer 27

Rifampin

Question 28

What is the MOA of rifampin ?

Answer 28

Inhibits MRNA synthesis

Question 29

fluoroquinolone MOA ?

Answer 29

Inhibits DNA gyrase function

Question 30

What is the first generation fluoroquinolone ?

Answer 30

Cipeofloxacin

Question 31

What are the second generation fluoroquinolones ?

Answer 31

Levofloxacin Gemifloxacin Moxifloxacin

Question 32

What are the protein inhibitor antibiotics ?

Answer 32

1) Macrolides (azithro-erythro-clorithro) 2) Clindamycin 3) Chloramphenicol 4) Lynezolid 5) Aminoglycosides ( gentamicin- Amikacin- tobramicin) 6) tetracyclines ( doxycycline- tetracycline)