Antibiotics Flashcards
Penicillins
Penicillin G
Methicillin
Nafcillin
Amoxicillin
1st generation Cephalosporins
Cefazolin (Ancef, Kefzol)
Does not penetrate BBB
Most gram + (staph and streptococci)
Cellulitis, abscesses, URI, UTI
2nd generation Cephalosporins
Cefuroxime (Ceftin, Zinacef) = Better gram – coverage
H-influenzae pneumonia, UTI, otitis media
Cefoxitin (Mefoxin)
Cefotetan (Cefotan)
3rd generation Cephalosporins
Cefotaxime (Claforan)=Some cross BBB
Better gram – than before; treats resistance
Meningitis
Ceftriaxone (Rocephin) = Gonorrhea
Ceftazidime (Fortaz)
4th generation Cephalosporins
Cefepime (Maxipime)= Most resistant to hydrolysis by lactamases
Usually reserved for multi-resistant organisms
Penetrates BBB well
Carbapenem
Ertapenem (Invanz)
Meropenem (Merrem)
Imipenem (Primaxin)
Aminoglycosides
Inhibit protein synthesis (Ribosomal and mRNA misread)
Gentamycin
Fluroquinolone
Inhibit DNA synthesis
Ciprofloxacin (Cipro)
Levofloxacin (Levaquin)