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Antibiotics > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

What is the treatement for H. pylori

A

Amoxicillin, PPI and clarithromycin

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2
Q

What is the treatment for common gut infections

A

Coliform - gentamicin
Enterococcus - amoxicillin
Anaerobes - metronidazole

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3
Q

What is metronidazole used for?

A

Anaerobic infections
Funky things - amoeba, protazoa etc

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4
Q

What is the treatment of a COPD exacerbation

A

Amoxicillin and doxycycline

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5
Q

What is the treatment of leigonella (pneumonia presenting with GI symptoms)

A

Macrolide (eryhtromycin etc)
Quinolone (levofloxacin)

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6
Q

What is the treatment of epiglottitis

A

Cefriaxone (cephlasporin)

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7
Q

What is the treatment of bordella pertussis

A

Macrolide

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8
Q

What is the treatment of staph aureus?

A

Flucloxacillin

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9
Q

What is the endocarditis treatment of strep viridans?

A

Benzylpenicillin and gentamicin

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10
Q

What is the endocarditis treatment of enterococcus?

A

Amoxicillin/vancomycin and gentamicin

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11
Q

What are the ABx treatments for any other endocarditis infections?

A

Vancomycin and IV gentamicin

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12
Q

What are the CAP pneumonia treatments?

A

Non-severe - amoxicillin IV
Severe - Co-amoxiclav IV and Clarithromycin IV (becomes doxycyclin)

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13
Q

What are the HAP treatments?

A

Non-severe - amoxicillin and metronidazole
Severe - GAM

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14
Q

What are the side effects of the TB drugs

A

Rifampicin - red secretions
Isonazid - Peripheral neuropathy
Pyrazinamide - hepatitis, nausea, vomiting, anorexia, joint pain
Ethambutol - colour blindness -> blindness

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15
Q

What are the treatment for latent Tb

A

RI for 3 months or I for 6 months if side effects e.g. oral contraceptive pill

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16
Q

What are the cell wall antibiotics and which ones are b-lactam ABX

A

Cephlasporins, carbapenems, penicillins - b-lactam
Glycopeptides - non b-lactam

17
Q

Are cell-wall abx bacteriostatic or bacteriocidal

A

Bacteriocidal

18
Q

What is cephlasporins compared to penicillins

A

More b-lactam resistant

19
Q

What antibiotics inhibit protein synthesis?

A

Aminoglycoside, tetracycline, macrolide, chloramphenicol, clindamycin

20
Q

Are protien synthesis abx bacteriostatic or cidal

A

Aminoglycosides are bacteriocidal, the others are bacteriostatic

21
Q

What is unique about the secretion of macrolides?

A

They are excreted via the liver/gut whereas most others are kidneys/urine

22
Q

What antibiotics inhibit folate synthesis?

A

Sulphonamides/trimethroprim

23
Q

What is the action of fluoroquinolone?

A

Inhibit DNA synthesis/replication

24
Q

What is the action of metronidazole?

A

Damage DNA

25
Q

What is the combination of co-trimoxazole and what can it be used for?

A

Sulphonamide + trimoxazole and can be used to treat AIDS exacerbation through pneumocystic jivorecci

26
Q

Catagorise these specific antibiotics: cefriaxone, vancomicin, gentamicin, erythromycin, ciprofloxacin

A

Cefriazone - cephlasporin
Vancomycin - glycopeptide
Gentamicin - aminoglycoside
Erythromycin - macrolide
Ciprofloxacin - quinolone

27
Q

What antibiotics cause C. diff

A

Cephlasporin, clindamicin, ciprofloxacin (quinolone), co-amoxiclav

28
Q

What is an indicative not-use of metronidazole

A

Alcohol interaction

29
Q

What is a common side effect of gentamicin

A

Renal damage
CN XIII damage

30
Q

What is a common side effect of quinolones?

A

Tendonitis

31
Q

What antibiotics are not safe in pregnancy?

A

Quinolones
Macrolides (erythromycin is)

32
Q

What is the treatment for pseudomonas?

A

Gentamicin

33
Q

When is doxycycline used?

A
  • 1st line atypical pneumonias
  • E.G. CHLAMYDIA PSITTACHI, COXIELLA BURNETTI
  • COPD exaccerbation
  • broad spectrum if allergic to penicillin
34
Q

Treatment of bronchiectasis

A

Macrolide and nebulised gentamicin

35
Q

What antibiotic may interact with amiodarone and warfarin

A

Erythromycin

Antibiotics (1 decks)

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