Antibiotics Flashcards by Jessica Sedinkin | Brainscape

Q

Cell wall synthesis abx

A

PCN, cephalosporins, carbopenems, vancomycin

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Q

30s ribosomal inhibitors

A

Tetracycline, amino glycosides, linezolid

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Q

50s ribosomal inhibitors

A

Erythromycin, clindamycin, cinercid

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Q

Inhibitors of DNA helicase

A

Quinolones

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Q

Produces oxygen radicals that break up DNA

A

Flagyl

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Q

How does PCN get resistances?

A

Plasmid transfer

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Q

How does MRSA get its resistance?

A

Mutation of cell wall binding protein

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Q

If your Peak is too high

A

Decrease the amount

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Q

If your trough is too high

A

Decrease frequency

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Q

What is a side effect of a third generation cephalosporin?

A

Cholestasis

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Q

What are the aminoglycosides?

A

Gentamicin and Tobramycin

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Q

What are the side effects of aminoglycosides?

A

Nephrotoxicity and ototoxicity

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Q

How does erythromycin work?

A

Works on motilin

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Q

What transplant med is a calcinurin inhibitor

A

Tacrolimus

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Q

What transplant med is a purine anti-metabolite

A

Mycofenilate mofitil

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Q

How do steroids work?

A

Prevent NFKB

Q

What are the side effects of amphotericine B?

A

Hypomag, hypokalemia, leukopenia, vfib, thrombocytopenia

Q

Side effect of silver sulfadiazine

A

Neutropenia

Q

Side effect of mafenide acetate

A

Metabolic acidosis
MA=MA

Q

Side effect of silver nitrate

A

HypoNa, hypoCl, hypoCa, hypoK