Antibiotics Flashcards
1
Q
Complication of long-term linezolid use?
A
Bone marrow suppression
2
Q
Empiric regimen of choice for osteomyelitis?
A
Vancomycin and 3rd or 4th gen cephalosporin
3
Q
Why is Vanc + Zosyn problematic?
A
Combo causes nephrotoxicity
4
Q
What is the complication of long-term clindamycin use?
A
C. Difficile infection
5
Q
How soon should antibiotics be given for osteomyelitis?
A
Whenever possible, antibiotics should be DELAYED until bone cultures can be obtained.
6
Q
What are the drugs of choice for gram (-) bacteria in osteomyelitis?
A
Fluoroquinolones because they penetrate bone well