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Farmacologia > Antibioticos > Flashcards

Antibioticos Flashcards

1
Q

Transporte llevado a cabo en el interior del vitreo

A

Difusión pasiva

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2
Q

Formas de eliminación de los antibioticos

A
  1. Difusión pasiva : a través del canal de Schlemm

2. Transporte activo: capilares y EPR

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3
Q

Características de los aminoglucosidos (tobramicina y gentamicina)

A

Epiteliotoxicos

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4
Q

Características del cloranfenicol

A

Daño reversible

Produce anemia aplasica

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5
Q

Mecanismo de la sulfonamida

A

Antagonista del ácido paraaminobenzoico para síntesis bacteriana de ácido folico

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6
Q

Polimixina es útil en que bacteria

A

Pseudomonas

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7
Q

La penicilina tiene mayor penetrancia si se administra con

A

Probenecid o en casos de inflamacion

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8
Q

Cefalosporina con buena penetrnacia en humor acuoso

A

Ceftazidima
Cefepime
Ceftriaxona
Cefotaxima

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9
Q

Mecanismo de las tetraciclinas

A

Inhiben la actividad de metaloproteinasas

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10
Q

Antibiótico producido por streptomyces

A

Tetraciclinas

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11
Q

Contraindicaciones de las tetraciclinas

A

Menos de 12 años

Junto con leche y antiacidos (quelantes del calcio)

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12
Q

Derivados fluorados del ácido nalidixico

A

Quinolonas

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13
Q

Derivados fluorados del ácido nalidixico

A

Quinolonas

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14
Q

Mecanismo de accion de las quinolonas

A

Inhiben la topoisomerasa II y IV

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15
Q

Mecanismo de las sulfonamidas

A

Antagonista competitivo para la síntesis bacteriana del ácido folico

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16
Q

Por que se da la resistencia

A

Producción de penicilasa

17
Q

Que produce el ciproflox

A

Depósitos córneas cristalinos-blancos ,desaparecen al interrumpirlos

18
Q

Efecto adverso de la neomicina

A

Epiteliopatia punteada

Retrasa reepitelizacion de las abrasiones

19
Q

Mecanismo de la vancomicina

A

Inhibe la polimerizacion de glucopeptidos

Deriva de cultivos de streptococo orientalis

20
Q

Efecto adverso de la amikacina

A

Toxicidad retiniana

21
Q

Tratamiento de la endoftlmitis

A

Vancomicima y aminoglucosidos

Farmacologia (17 decks)

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