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Clinical Pharmacotherapeutics > Antibiotic therapies by drug class > Flashcards

Antibiotic therapies by drug class Flashcards

1
Q

Which drugs weaken cell walls?

A 
PCNs
Cephalosporins
Carbapenems
Fosfomycin
Vancomycin
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2
Q

Which drugs inhibit protein synthesis?

A

Macrolides
Tetracyclines
Ketolides
Lincosamides (clindamycin)

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3
Q

Which drugs inhibit bacterial DNA synthesis?

A

Fluoroquinolones

Metronidazole

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4
Q

Which drugs compete for folic acid

A

Sulfonamides

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5
Q

Codes from class; SSE

A

strep, staph enterococcus (gm + cocci)

skin, soft tissue, respiratory

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6
Q

Codes from class: EKP

A

E coli, Klebsiella, Proteus (gr - bacilli)

UTI, GI

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7
Q

Codes from class: EbSP

A

enterobacter, serratia, providencia, salmonella, shigella
(gr - bacilli)

GI

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8
Q

Non-grouped gram - cocci

A

H. flu, Moraxella - AOM, sinusitis, bronchitis

Neisseria - GU, meningitis

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9
Q

Penicillins

A

Gram + (SSE)

skin, soft tissue, respiratory

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10
Q

Penicillin extended spectrum (+ BLIC)

A

Less gram +, more gram - (EKP, EbSP)

GI, GU, Skin, soft tissue, resp

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11
Q

Tetracyclines
Doxycycline
Minocycline

A

Gr+ strep pneumoniae, Gr -, atypicals, MRSAl, chlamydiae, mycoplasma, rickettsiae, protozoan parasites

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12
Q

Sulfonamide

TMP-SMZ

A

Gr- (EKP)

MRSA

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13
Q

1st gen cephalosporins

A

Gr + (SSE)

resp/skin/soft tissue

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14
Q

2nd gen cephalosporins

A

Gr +, weak Gr - (SSE)

respiratory

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15
Q

3rd gen cephalosporins

A

Weak gr +, good gr -

B lactamase, H-flu, EKP, ESP

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16
Q

4th gen cephalosporins

A

B lactamase, enhanced Gr -, polymicrobial infections

EbSP, EKP, SSP

17
Q

2nd gen fluoroquinolone - Cipro

A

Weak gr +, good gr -; pseudomonas

GU (UTI), psuedomonas

18
Q

3rd gen fluoroquinolone - levofloxacin

A

Gr +, Gr -, atypicals, B lactamase, DRSP, anaerobes, pseudomonas

Resp, GU, pseudomonas

19
Q

4th gen fluoroquinolone - moxifloxacin, gemifloxacin

A

atypicals, B lactamase, Pseudomonas, DRSP, MRSA, anaerobes

GU, skin, resp

20
Q

macrolides

A

Gr+ (SS), some gr - (Neisseria, H. flu)

Resp, skin GU

21
Q

ketolide

telithromycin (2nd gen macrolide)

A

Gr+, Gr-, atypicals, DRSP

22
Q

pseudomonas

A

aminoglycoside, B lactam, fluoroquinolone, 3rd gen cephalosporin

23
Q

Bacteroides (aspiration GI)

A

carbapenems, clindamycin, tetracycline

Clinical Pharmacotherapeutics (3 decks)

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