Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Antibiotics > Antibiotic Targets > Flashcards

Antibiotic Targets Flashcards

1
Q

Penicillin G and V target..

A

Gram +, anaerobes, spirochete, very weak gram -

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Amoxicillin and ampicillin target

A

Gram +, Gram -, anaerobes, spirochetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Nafcillin, others target

A

Non-MRSA staph

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Piperacillin targets

A

Pseudomonas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Vancomycin targets

A

Gram + & anaerobes. especially MRSA and severe or recurrent C. dif

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Aminoglycosides (Gentamicin, Streptomycin) target

A

Gram +, Gram- aerobes only

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Chloramphenicol targets

A

Some Gram -, anaerobes, intracellular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Clindamycin (Lincosamide) targets

A

Gram + & anaerobes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Linezolid targets

A

Gram +

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Macrolides (Azithromycin, Telithromycin) target

A

some gram +, Gram -, intracellular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Streptogramins (Quinopristin, Dalfopristin) target

A

Gram +

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Tetracyclins (Doxycyclin, Tigecyclin) target

A

Gram +, Gram -, intracellular, spirochetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Fluoroquinolones (Ciprofloxacin, Moxifloxacin) target

A

Gram +, Gram -, intracellular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Moxifloxacin targets

A

Better for Gram +

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Ciprofloxacin targets

A

Better for Gram -

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Metronidazole targets

A

Anaerobes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Sulfomethoxazole-Trimethaprim targets

A

Gram +, Gram -, Intracellular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Aztreonam (monobactam) targets

A

Gram -

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Carbapenems (Impenem) target

A

Gram +, Gram -, Anaerobes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Cephalosporins target

A

Gram +, Gram -, Spirochetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Colistin (polymyxin) targets

A

Gram -

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Daptomycin targets

A

Gram +

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Clostridium difficile

A

1) Metronidazole

2) Vancomycin (severe recurrent disease)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Mycobacterium tuberculosis

A

1) First-line: isoniazid, rifampin, pyrazinamide, ethambutol

2) Second-line: ethonamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Staphylococcus aureus (methicillin sensitive)

A
  1. ) Nafcillin

2. ) cefazolin, clindmycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Staphylococcus aureus (methichillin resistent)

A
  1. ) Vancomycin
  2. ) CA: sulfamethoxazole/trimethoprim, ceftaroline, clindamycin.
  3. ) Alternatives to vancomycin: daptomycin, linezolid, quinuprisitn/dalfopristin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Adverse effects of Aminoglycosides

A

Ototoxicity, Vestibular toxicity, Nephrotoxicity, Neuromuscular block

28
Q

Adverse effects of Chloramphenicol

A

Hematological, Gray baby syndrome,

29
Q

Adverse effects of Clindamycin

A

Diarrhea, hematological, neuromuscular block

30
Q

Adverse effects of Linezolid

A

Peripheral neurotoxicity, Hematological

31
Q

Adverse effects of Macrolids

A

Cardiac arrhythmias

32
Q

Adverse effects of Streptogramins

A

Arthralgia, myalgia, injection site irritation

33
Q

Adverse effects of Telithromycin

A

Neuromuscular block, cardiac arrhythmias, hepatotxicity

34
Q

Adverse effects of Tetracyclines

A

Gastrointestinal, nephrotocicty, photosensitivity, hepatotoxicity, Deposition in teeth and bones undergoing calcification.

35
Q

Adverse effects of Aztreonam

A

Injection site irritation

36
Q

Adverse effects of Cephalosporins

A

Hypersensitivity, Nephrotoxicity

37
Q

Adverse effects of Fluoroquinolones

A

Tendinopathies, prolong cardiac QT interval, lower seizure threshold, peripheral neuropathy, neuromuscular block

38
Q

Adverse effects of Metronidazole

A

ethanol intolerance

39
Q

Adverse effects of Sulfamethoxazole & Trimethoprim

A

Bilirubin displacement and kernicturus in neonates, Hypersensitivity, hemolytic anemia, Stevens-Johnson syndrome

40
Q

Adverse effects of Isoniazid

A

Hepatotoxicty, perpheral neuropathy

41
Q

Adverse effects of Rifampin

A

Hepatotoxicity, Flu-like syndrome, orange-colored excretions

42
Q

Adverse effects of Ethambutol

A

Optical Neuritis

43
Q

Adverse effects of Pyrazinamide

A

most hepatotoxic antiTB, Hyperuricemia

44
Q

Adverse effects of Ethionamide

A

Hepatotoxicity, GI irritations, sedation, depression

45
Q

Antibiotics that are cytochrome P450 inhibitors

A

1) Chloramphenicol
2) Ciprofloxacin (not moxifloxacin)
3) Macrolides (not azithromycin)
4) Quinupristin/dalfopristin

46
Q

Antibiotics that are cytochrome P450 inducers

A

1) Rifampin

47
Q

Antibiotics whose oral bioavailability is decreased by multi-valent cations

A

1) Doxycycline (other tetracyclines are worse)
2) Fluroquinolones
3) Isoniazid

48
Q

B-lactams

A

Penicillins, cephalosporins, carbapenems, monobactams. Target cell wall

49
Q

Cephalosporins

A
  1. ) Cefazolin
  2. ) Ceftriaxone
  3. ) Cefepime
  4. ) Ceftaroline
50
Q

Carbapenems

A

Imepenem (with cilastatin)

51
Q

Monobactams

A

Azitreonam

52
Q

B-lactamase inhibitors

A

Clavunic acid

53
Q

Glycopeptidases

A

Vancomycin

54
Q

Lipopeptidase

A

Daptomycin

55
Q

Polymyxins

A

Colistin

56
Q

Aminoglycosides

A

Gentamicin, Streptomycin

57
Q

Tetracyclins

A

Doxycyclin, Tigecyclin

58
Q

Lincosamides

A

Clindomycin

59
Q

Macrolides

A

Azithramycin, Telithromycin

60
Q

Streptogramins

A

Quinopristin, Dalfopristin

61
Q

Fluoroquinolones

A

Ciprofloxacin, Moxifloxacin

62
Q

Sulfonamides

A

Sulfamethoxazole

63
Q

Dihydrofolate Reductase Inhibitor

A

Trimethoprim

64
Q

Cefazolin targets

A

Gram +

65
Q

Ceftriaxone

A

Gram -

66
Q

Cefepime

A

Gram - & Pseudomonas

67
Q

Ceftaroline

A

CA pneumonia, some MRSA

Antibiotics (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions