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Week 57: Nausea and Vomiting > Antibiotic Review > Flashcards

Antibiotic Review Flashcards

1
Q

IV antibiotics are used in which 3 circumstances

A

Patients who cannot take oral antibiotics
Times when there is no oral option
Critically ill patients

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2
Q

Abx that are >90% bioavailable

A 
Doxycycline
Fluoroquinolones
Metronidazole
Linezolid
Rifampin
TMP-SMX
Fluconazole
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3
Q

Drug of choice for B-hemolytic strep

A

Penicillin

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4
Q

Drug of choice for Strep pneumo

A

Amoxicillin/Penicillin

Ceftriaxone/Cefuroxime

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5
Q

Drug of choice for viridans group strep

A

Penicillin

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6
Q

Drug of choice for listeria

A

Ampicillin

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7
Q

Drug of choice for enterococcus

A

Ampicillin/amoxicillin

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8
Q

Drug of choice for MSSA

A

Cloxacillin

Cephalexin/Cefazolin

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9
Q

Drug of choice for MRSA

A

Vancomycin

Also daptomycin, linezolid, TMP-SMX, doxycycline

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10
Q

Vancomycin mechanism and adverse effects

A

Inhibits peptidoglycan synthesis by preventing elongation and crosslinking (disrupts bacterial cell wall) - only for GRAM +
AE: nephrotoxicity, Red Man Syndrome, rash, cytopenias

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11
Q

Beta lactamase

A

Major resistance mechanism in gram - pathogens

Can inactivate the beta lactams

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12
Q

4 times you need to worry about gram - pathogens

A

Lower GI and GU infections
Haemophilus influenzae
Nosocomial infections
Chronic wound infections with previous abx therapy

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13
Q

Drug of choice for enterobacteriaceae

A

Pip-Tazo
Amox-Clav
Carbapenems
Ceftriaxone

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14
Q

Drug of choice for ESBL

A

Carbapenems

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15
Q

Drug of choice for N. gonorrheae

A

Ceftriaxone/cefixime AND azithromycin

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16
Q

Drug of choice for Pseudomonas

A

Pip-Tazo
Carbapenems
Ceftazidime
Ciprofloxacin

17
Q

Drug of choice for H influenzae

A

Amox-clav
Ceftriaxone/Cefuroxime
Fluoroquinolones

18
Q

Preferred empiric anaerobic therapy for

  1. Above the diaphragm
  2. Below the diaphragm
A
  1. Clindomycin or metronidazole

2. Metronidazole

Week 57: Nausea and Vomiting (7 decks)

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