Antibiotic mechanisms Flashcards

0
Q

Ceftriaxone mechanism. Cross BBB?

A

Binds to penicillin binding protein to inhibit cell wall synth
Yes crosses BBB

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1
Q

Amoxicillin/Ampicillin mechanism

A

Cell wall inhibitor bind to PBP

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2
Q

Aztreonam mechanism

A

PBP inhibiting, can’t be broken by beta lactamases

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3
Q

Vancomycin mechanism

A

Cell wall inhibitor binds to D-ala-D-ala shielding it from transpeptidation reaction

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4
Q

Rifampin mechanism

A

Inhibits DNA dependent RNA polymerase, increasing P450 levels decreasing activity of other drugs

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5
Q

Gentamicin and amikacin mechanism

A

Protein synthesis inhbitor, bind to 30S subunit

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