Antibiotic Man (Hospital)

Question 1

CNS

Answer 1

• Meningitis:

Ceftriaxone + Dexamethasone

Question 2

ENT

Answer 2

Epiglottitis/Supraglottitis:

- Cextriaxone

Question 3

Pneumonia

Answer 3

• CAP:

Mild/Moderate: Amoxicillin
Severe: Co-amoxiclav + Doxycycline
ICU/HDU/NBM: Co-amoxiclav + Clarithromycin

• HAP:

Non-Severe: PO Amoxicillin
Severe: IV Amoxicillin + Gentamicin

• Aspiration

Non Severe: Amoxicillin + Metronidazole
Severe: Amoxicillin + Metronidazole + Gentamicin

• Acute Exacerbation of COPD (or acute bronshitis/cough in the elderly):
  Amoxicillin (doxy if no effect)

Question 4

Heart

Answer 4

• Endocarditis

Native Valve (indolent/subacute): 
amoxicillin + gentamicin

Native Valve (severe/Sepsis):
Flucloxacillin

Prosthetic Valve or Suspected MRSA:
Vancomycin and Gentamicin

Question 5

GI

Answer 5

• C.Diff

Non Severe: Metronidazole
Severe: Vancomycin +/- Metronidazole

• Peritonitis/Biliary Tract/Intra-abdominal

IV amoxicillin + Metronidazole + Gentamicin

• Proven Spontaneous Bacterial Peritonitis

Mild: Co-trimoxazole
Severe: Piperacillin/Tazobactam

Question 6

GU

Answer 6

• Uncomplicated Female Lower UTI OR Uncatheterised Male UTI:

Nitrofurantoin or Trimethoprim

• Complicated UTI/Pyelonephritis/Urosepsis:

Amoxicillin + Gentamicin

Question 7

Bone/Skin

Answer 7

• Cellulitis/Acute Septic Arthritis/Osteomyleitis:

Flucloxacillin

• Open Fracture Prophylaxis:

Cefuroxime

• Diabetic Foot Infection:

Mild: Flucloxacillin or Doxycyxline
Moderate: Flucloxacillin or Doxycycline AND Metronidazole

Question 8

Severe Systemic Infection Unknown Source

Answer 8

Amoxicillin + Metronidazole + Gentamicin

if Pen allerg:

Vancomycin + Metronidazole + Gentamicin