Antibiotic Man Flashcards
What is the antibiotic of choice in Meningitis?
IV Ceftriaxone 2g bd
What additional drug can you give in addition to antibiotics in meningitis?
Dexamethasone IV 10mg qds
When can steroids be given in addition to antibiotics in the treatment of meningitis?
Ideally started with or just before first dose of antibiotics for 4 days.
If you are considering treatment of meningitis in the elderly or immunocompromised, what additional antibiotic would you add?
IV Amoxicillin 2g 4 hourly
What is the treatment of Epiglottitis?
IV Ceftriaxone 2g od
What is the CURB65 score
Confusion Urea >7mmol/L Resp Rate > 30 Blood pressure <90/60 >65
What is the antibiotic of choice for mild/moderate CAP?
Amoxicillin 1g tds IV/PO
What is the antibiotic of choice for mild/moderate CAP if penicillin allergic?
Doxycycline PO 200mg on day 1 then 100mg od.
OR IV Clarythromycin
How long is the treatment duration for mild/moderate CAP/HAP?
5 days.
What is the antibiotic of choice for severe CAP (non HDU)?
Co-Amoxiclav IV 1.2g tds + Doxycycline PO 100mg bd
What is the antibiotic of choice for severe CAP (HDU)
Co-Amoxiclav IV 1.2g tds + Clarythromycin IV 100mg bd
What is the antibiotic of choice for severe CAP if penicillin allergic?
Levofloxacin IV 500mg bd
What is the duration of treatment for severe HAP/CAP?
7 days
What is the antibiotic of choice for non-severe HAP?
PO Amoxicillin
What is the antibiotic of choice for non-severe HAP if penicillin allergic?
Doxycycline 100mg bd
What is the antibiotic of choice for Severe HAP?
IV Amoxicillin + Gentamicin
What is the antibiotic of choice for Severe HAP if penicillin allergic?
IV Co-trimoxazole + Gentamicin
What are the typical antibiotics of choice in aspiration pneumonia?
PO Amoxicillin + Metronidazole
What additional antibiotic do you add for a severe aspiration pneumonia?
IV Amoxicillin + Metronidazole + Gentamicin
What is the antibiotic of choice for acute exacerbation of COPD?
Amoxicillin 500mg tds 5 days
What is the antibiotic cocktail indicated for subacute endocarditis?
IV Amoxicillin + Gentamicin
What is the antibiotic cocktail indicated for acute endocarditis?
IV Flucloxacillin
What is the antibiotic cocktail indicated for prosthetic valve/MRSA endocarditis?
IV Vancomycin + Gentamicin + Rifampicin
What is the antibiotic of choice for non-severe C. Diff infection?
PO Metronidazole 400mg tds 10days
What is the antibiotic of choice for severe C.Diff
PO Vancomycin 125mg qds 10 days
How does one distinguish between severe and non-severe C.Diff?
Temperature >38.5 Colonic dilatation >6cm / ileus WBC > 15x10^9 Creatinine >1.5x baseline. Persistient CDI despite 2 courses of appropriate therapy.
What is the antibiotic of choice for treating recurrent C.Diff (within 8 weeks of treatment)
Fidaxomicin 200mg bd
What is the antibiotic of choice for mild spontaneous bacterial peritonitits?
Co-trimazole PO
What is the antibiotic of choice for severe spontaneous bacterial peritonitis?
Pipercilin/Tazobactam IV
What is the antibiotic of choice for complicated UTI/pylonephritis/urosepsis?
IV Amoxcillin + Gentamicin
What is the antibiotic of choice & duration for uncomplicated female UTI?
Nitrofurantoin 100mg MR bd OR
Trimethopirm 200mg bd for 3 days
What is the antibiotic of choice & duration for uncomplicated male UTI?
Nitrofurantoin 100mg MR bd OR
Trimethopirm 200mg bd for 7 days
What is the antibiotic of choice in treating acute bacterial prostatits or epididymoorchitis?
Depends if there is a suspicion of STI. If so, Doxycycline. If not, Ofloxacin.
What is the antibiotic of choice for open fracture prophylaxis?
IV Co-Amoxicilav 1.2g tds to be started within 3 hours for 72 hours