Antibiotic Man Flashcards
Tx for Meningitis
Ceftriaxone IV 2g bd
plus
Dexamethasone IV 10mg qds
Tx for Meningitis if encephalitis is suspected
Aciclovir IV 10mg/kg
Tx for Meningitis if over 60 or immunocompromised
Ceftriaxone IV 2g bd
plus
Dexamethasone IV 10mg qds
ADD
Amoxicillin IV 2g 4 hourly
Tx for epiglottitis
Ceftriaxone IV 2g od
CAP Tx for CAP 0-2
Amoxicillin 1g tds PO/IV = 5 days
CAP Tx for CAP 0-2 if pen. allergic
Doxycyline PO 200mg on day 1
then 100mg od
or IV Clarithromycin
CAP Tx for CAP 3-5
Co-amoxiclav IV 1.2g tds
AND
Doxycycline PO 100mg bd
for 7 days
CAP Tx for CAP 3-5 if pen. allergic
IV Levofloxacin 500mg bd
CAP Tx for CAP 3-5 and in ICU
Co-amoxiclav IV 1.2g tds
AND
Clarithromyin IV 500mg bd
Tx for non-severe HAP
PO Amoxicillin
5 days
Tx for non-severe HAP if pen. allergic
Doxycycline 100mg bd
Tx for severe HAP
IV Amoxicillin + Gentamicin
7 days
Tx for severe HAP if pen. allergic
IV Co-trimoxazole + Gentamicin
Tx for non-severe aspiration pneumonia
PO Amoxicillin + Metronidazole
5 days
Tx for non-severe aspiration pneumonia if pen. allergic
PO Doxycycline 100mg bd + Metronidazole
5 days
Tx for severe aspiration pneumonia
IV Amoxicillin + Gentamicin + Metronidazole
Tx for severe aspiration pneumonia if pen. allergic
Replace Amoxicillin with PO Doxycycline or IV Clarithromycin
Step down Tx for severe aspiration pneumonia
PO amoxicillin + metronidazole
Total = 7 days
Tx of acute exacerbation of COPD - 1st and 2nd line
Only give antibiotics if increased sputum purulence
or consolidation on CXR
1st line = Amoxicillin 500mg tds
2nd line = Doxycycline 200mg on day 1 then 100mg od
Total = 5 days
Protocol for suspected endocarditis
- take appropriate blood cultures
- start empirical therapy and refer to ID/Microbiology
- check endocarditis specific guidance/guidelines
Tx for native value (subacute) endocarditis
Amoxicillin IV 1g 4 hourly
AND
Gentamicin 1mg/kg bd
Tx for native value severe sepsis (acute) endocarditis
Flucloxacillin IV 2g 6 hourly
Tx for prosthetic value or suspected MRSA endocarditis
Vancomycin IV
AND
Gentamicin IV 1mg/kg
And
Rifampicin PO 600mg bd
C Diff Tx - non severe
Metronidazole PO 400mg tds
10 days
C Diff Tx - severe
Vancomycin 125mg qds PO
+/-
IV Metronidazole
10 days
Tx for Peritonitis/Biliary Tract/Intra-abdominal
IV Amoxicillin + Metronidazole + Gentamicin
Total = 7 days
Step down Tx for Peritonitis/Biliary Tract/Intra-abdominal
PO Co-Trimoxazole + Metronidazole
Tx for Peritonitis/Biliary Tract/Intra-abdominal if pen. allergic
IV Vancomycin + Metronidazole + Gentamicin
Guidelines for Catheterised patient with UTI or UTI in older adults
do not use urinalysis
do not Tx unless clinical signs/Sx of infection
if definite infection Tx as per complication UTI
Tx for complicated UTI/Pyelonephritis/Urosepsis
IV Amoxicillin + Gentamicin
Total = 7 days
Step down Tx for complicated UTI/Pyelonephritis/Urosepsis
PO Co-trimoxazole
Tx for complicated UTI/Pyelonephritis/Urosepsis if pen. allergic
IV Co-trimoxazole + Gentamicin
Tx for uncomplicated female lower UTI
Nitrofurantoin 500mg qds
OR
Trimethoprim 200mg bd
Total = 3 days
Tx for uncathetherised Male UTI
Nitrofurantoin 500mg qds
OR
Trimethoprim 200mg bd
Total = 7 days
Tx for Cellulitis
Flucloxacillin 1g qds
Total = 7 days
Tx for Cellulitis if pen. allergic
Doxycycline 100mg bd PO
Open fracture prophylaxis
IV Co-Amoxiclav 1.2g tds
or IV Co-Amoxiclav 960mg bd + Metronidazole 500mg tds
what time frame should open fracture prophylaxis be started within
within 3 hours for max 72 hours
mild diabetic foot infection Tx
Flucloxacillin 1g qds or Doxycycline 100mg bd
moderate diabetic foot infection Tx
Flucloxacillin 1g qds + Metronidazole 400mg tds
OR
Doxycycline 100mg bd + Metronidazole 400mg tds
Tx for acute septic arthritis/osteomyelitis
IV Flucloxacillin 2g qds
Tx for severe systemic infection w/ unknown source
IV Amox. + Metronidazole + Gent
Tx for severe systemic infection w/ unknown source if IVDU
IV Amox. + Metronidazole + Gent + Flucloxacillin
to cover S. aureus
Tx for severe systemic infection w/ unknown source and pen. allergic
IV Vancomycin + Metronidazole + Gent
if neutropenic sepsis is suspected, what Ix should be done
Blood cultures Stool Cultures MSU Sputum culture CXR Swab skin lesions Swab Hickman line exit site Throat swab
Tx for Neutropenia + Sepsis + News less or equal to 6
standard risk patients
Piperacillin/Tazobactam
(if pen allergic = Teicoplanin + Aztreonam)
(if anaphylaxis or angioedema = Tecioplanin + Ciprofloxacin)
Tx for Neutropenia + Sepsis + News more than or equal to 7
high risk patients
Piperacillin/Tazobactam + Gentamicin
(if pen allergic = Teicoplanin + Aztreonam + Gentamicin)
(if anaphylaxis or angioedema = Tecioplanin + Ciprofloxacin + Gentamicin)
