antibiotic interactions Flashcards
1
Q
enzyme inhibitors
A
erythromycin, clarithromycin, isoniazid, metronidazole, ciprofloxacin
2
Q
enzyme inducers
A
rifampicin
3
Q
absorption
A
absorption of tetracyclines and quinolones reduced by antacids/calcium
4
Q
Broad-spectrum antimicrobials and oral contraceptives
A
entero-heptic cycling can lead to contraceptive failure
5
Q
Broad-spectrum antimicrobials and warfarin
A
increased INR
6
Q
Metronidazole
A
disulfiram-like interaction with alcohol
7
Q
Aminoglycosides/glycopeptides/colistin with loop diuretics or ciclosporin or tacrolimus
A
nephrotoxicity
8
Q
quinolones and steroids
A
tendonitis
9
Q
quinolones and NSAIDs
A
convulsions
10
Q
Macrolides/quinolones
A
Q-T prolonging drugs