Antibiotic drugs, moa, coverage

Question 1

Penicillin G

Answer 1

IV (no e- withdrawing group)

streptococcus, NEVER staph

Question 2

Penicillin v/k

Answer 2

oral

streptococcus, NEVER staph

Question 3

Oxacillins

Answer 3

oral

staph only

Question 4

nafcillin

Answer 4

staph only

Question 5

ampicillin

Answer 5

gram+

susceptible to beta-lactamase

Question 6

amoxicillin

Answer 6

gram+

susceptible to beta-lactamase

Question 7

ticarcillin

Answer 7

gram-

pseudomonas

Question 8

piperacillin

Answer 8

good gram -/+
pseudomonas
enterococci
anaerobes

Question 9

imipenem/meropenem

Answer 9

some gram+
broad gram-
pseudomonas

Question 10

ertapenem

Answer 10

some gram+
broad gram-
NO pseudomonas, enterococcus, acinetobacter

Question 11

aztreonam

Answer 11

gram-
enterobacteriacea
pseudomonas

Question 12

beta lactam drugs

Answer 12

penicillins
penems
aztreonam
cephalosporins
clavams

Question 13

1st gen cephalosporins

Answer 13

cephalexin
cefazolin
cefadroxil

Question 14

1st gen cephalosporin coverage

Answer 14

broad gram+

no MRSA

Question 15

2nd gen cephalosporins

Answer 15

cefuroxime
cefoxitin
cefproxil

Question 16

2nd gen cephalosporin coverage

Answer 16

broad gram+

some e. coli and klebsiella

Question 17

3rd gen cephalosporins

Answer 17

ceftriaxone
cefixime
cefpodoxime
cefdinir
cefotaxime
ceftazidime

Question 18

3rd gen cephalosporin coverage

Answer 18

some gram+

good for gram- besides pseudomonas

Question 19

3rd gen cephalosporin with pseudomonas coverage

Answer 19

ceftazidime

Question 20

4th gen cephalosporin

Answer 20

cefepime

Question 21

4th gen cephalosporin coverage

Answer 21

some gram+
good gram- including pseudomonas
no anaerobes

Question 22

vancomycin

Answer 22

glycopeptide
great gram+
MRSA
C. diff

Question 23

quinolones

Answer 23

ciprofloxacin
levofloxacin
moxifloxacin

Question 24

quinnolones moa

Answer 24

dna gyrase inhibitor

Question 25

quinolone coverage

Answer 25

good gram- cipro pseudomonas moxi anaerobes levo best gram+

Question 26

trimethoprim moa

Answer 26

inhibits tetrahydrofolic acid production

Question 27

sulfamethoxazole moa

Answer 27

inhibits dihydropteroic acid production

Question 28

tetracyclines moa

Answer 28

ribosome inhibitors at 30s

Question 29

tetracyclines coverage

Answer 29

good gm+ active against MRSA tigecycline active against VRE/anaerobes

Question 30

macrolides

Answer 30

erythromycin clarithromycin azithromycin

Question 31

macrolides moa

Answer 31

ribosome inhibitors at 50s

Question 32

macrolides coverage

Answer 32

streptococcus some gm- atypicals

Question 33

side effect of erythromycin

Answer 33

GI cramping

Question 34

side effect of clarithromycin

Answer 34

metallic taste

Question 35

clindamycin moa

Answer 35

ribosome inhibitor at 50s

Question 36

clindamycin coverage

Answer 36

good gm+ | anaerobes

Question 37

clindamycin adverse effect

Answer 37

c. diff infection

Question 38

linezolid moa

Answer 38

inhibits ribosome at 50s

Question 39

linezolid coverage

Answer 39

MRSA | VRE

Question 40

linezolid side effects

Answer 40

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