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Antibiotics > Antibiotic Coverage > Flashcards

Antibiotic Coverage Flashcards

1
Q

Penicillin G/V

A 
Streptococcus
Enterococcus faecalis
Some oral anaerobes
Clostridium
N. meningitidis
Syphilis (Trepnoema pallidum)
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2
Q

Cloxacillin

A

Staph aureus (MSSA)
Staph epidermidis
Streptococci (some coverage)

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3
Q

Ampicillin/Amoxicillin

A 
Streptococcus
Enterococcus
E. coli
Proteus
H. influenzae
Listeria
NOT - Klebsiella
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4
Q

Amoxicillin/Clavulanic acid (Clavulin)

A 
Streptococcus
Enterococcus
E. coli
Proteus
H. influenzae
Listeria

Staph aureus
Klebsiella
M. catarrhalis
Bacteroides (gut anarobes)

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5
Q

Piperacillin, Ticarcillin

A

Ampicillin Coverage +
PEcK
+/- Bacteroides (gut anarobes)
SPACE/SPICE bugs - but develop resistance during therapy!

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6
Q

Piperacillin/Tazobactam

Ticarcillin/Clavulanate

A 
PEcK
Staph aureus (MSSA)
H. influenzae
M. catarrhalis
Oral and gut anarobes
SPACE and SPICE - still develop resistance
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7
Q

1st Gen Cephalosporins
Cefazolin - IV (Ancef)
Cephalexin - PO (Keflex)

A

Staph aureus
Most Streptococci
PEcK
Some oral anaerobes

NOT: H. influenzae, M. catarrhalis, gut anarobes, SPACE/SPICE

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8
Q

2nd Gen Cephalosporins
Cefuroxime - IV/PO
Cefaclor
Cefprozil - PO

A 
Less Staph coverage
Streptococci
PEcK
H. influenzae
M. catarrhalis
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9
Q

2nd Gen Cephalosporin + Anaerobic coverage

Cefoxitin - IV

A 
Less Staph coverage
PEcK
H. influenzae
M. catarrhalis
Anaerobic coverage (increasing resistance in Bacteroides)
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10
Q

3rd Gen Cephalosporin
Cefotaxime - IV
Ceftriaxone - IV
Cefixime - PO

A

Streptococci coverage
PEcK
H. influenzae
M. catarrhalis

NOT: SPACE/SPICE infections

!!BEST penetration into CNS!!!

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11
Q

3rd Gen Cephalosporin + Pseudomonas

Ceftazidime

A

Good GN coverage
Less GP coverage
P. aeruginosa

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12
Q

4th Gen Cephalosporin

Cefepime - IV

A

Good GP coverage - Staph and Strep
Good GN coverage (including P. aeruginosa)
More stable vs BLs of SPACE/SPICE bugs

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13
Q

Ertapenem

A 
Staph aureus (MSSA)
Streptococci
\+/- Enterococcus (faecalis)
Good GN Coverage - SACE/SICE
Good anaerobic coverage
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14
Q

Meropenem
Imipenem
Doripenem

A 
Staph aureus (MSSA)
Streptococci
\+/- Enterococcus (faecalis)
Good GN Coverage - SACE/SICE
Good anaerobic coverage

P. aeruginosa coverage (unlike ertapenem)

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15
Q

Vancomycin

A 
Staph aureus (MRSA)
Staph epidermidis (and other CN Staph)
Streptococcus
Enterococcus
C. difficile (PO treatment only)
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16
Q

Gentamicin
Tobramycin
Amikacin

A

GN coverage only
SPACE/SPICE

NO: anaerobic coverage

17
Q

Clarithromycin (Biaxin) - PO

Azithromycin (Zithromax) - IV/PO

A

Staph aureus
Streptococci
H. influenzae
M. catarrhalis

ATYPICALS:
Mycoplasma
Chlamydophilia
Legionella
N. gonorhoeae
B. pertussis
Lyme disease
Campylobacter
H. pylori
MAC - Mycobacterium avium intracellulare complex (HIV)

NOT: Enterococcus, GN bacilli, anaerobiccoverage

18
Q

Erythromycin - PO/IV

A

Staph aureus
Streptococci

ATYPICALS:
Mycoplasma
Chlamydophilia
Legionella
N. gonorhoeae
B. pertussis
Lyme disease
Campylobacter
H. pylori
MAC - Mycobacterium avium intracellulare complex (HIV)

NOT: Enterococcus, GN bacilli, anaerobiccoverage

19
Q

Tetracycline
Doxycycline
Minocycline

A

Staph aureus
Streptococcus
H. influenzae
M. catarrhalis

ATYPICALS:
Mycoplasma
Chlamydophilia
Legionella

MISC:
B. burgdorferi, Rickettsiae
NOT: Enterococci

20
Q

Tigecycline - IV

A 
Staphylococcus (including MRSA)
Streptococci
Enterococci (including VRE)
Most GN - Except Proteus, Pseudomonas, Providencia
Gut anarobes
Atypicals
21
Q

Ciprofloxacin (Cipro)
Levofloxacin (Levaquin) - for respiratory infections
Moxifloxacin (Avelox)

A 
PEcK
H. influenzae
M. catarrhalis
SPACE/SPICE - (most active vs P. aeruginosa)
N. gonorrhoeae
Salmonella
Shigella
Staph aureus (MSSA)
Streptococci
ATYPICALS:
Mycoplasma penumoniae
Chlamydophilia pneumoniae
Legionella pneumophilia

** Moxifloxacin - also anaerobic coverage
Unreliable: Enterococci
NOT recommended for GP infections

22
Q

TMP-SMX (Septra)

A 
Staph aureus (Including MRSA)
Strep pneumoniae
Listeria
Norcardia
PEcK
H. influenzae
M. catarrhalis
SICE/SACE (NOT P. aeruginosa)
S. maltophilia
B. cepacia

NOT: Enterococci

23
Q

Clindamycin

A

Staph aureus
Streptococcus
Anaerobes

NOT: Enterococcus

24
Q

Metronidazole

A

Anaerobes (including C. difficile)

Others - Protozoa

25
Q

Linezolid - PO/IV

A

Only GP coverage
Staphylococcus (including MRSA)
Streptococcus (including PRSP)
Enterococcus (including VRE)

Lacks GN activity

**Side effects - BM suppression and neuropathy; interacts with MAO

26
Q

Daptomycin - IV

A

Only GP Coverage
Staphylococcus (including MRSA)
Streptococcus
Enterococcus (including VRE)

NOT for GN infections

Antibiotics (7 decks)

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