Antibiotic Classes RECAP

Question 1

What is a beta lactam antibiotic + give an example?

Answer 1

beta-lactam antibiotics block cell wall synthesis by interfering with peptidoglycan production by binding to the transpeptidase enzymes

Question 2

Which classes of antibiotic do clarithromycin and gentamicin belong to?

Answer 2

protein synthesis inhibitors
Clarithromycin = macrolide
Gentamicin = aminoglycoside

Question 3

Which part of the bacterial cell does vancomycin work on?

Answer 3

binds to side-chains - blocking the cross-linking

glycopeptide.

Question 4

What are the main groups of antifungal drugs and how do they work?

Answer 4

Echinocandins
Azoles
Polyenes

Question 5

Which antibiotics act on the 30s ribosomal subunit?

Answer 5

Tetracyclines

Aminoglycosides

Question 6

Name two antibiotic combinations that feature a beta-lactamase inhibitor?

Answer 6

Co-amoxiclav

amoxicillin + clavulanic acid

Question 7

List three examples of human mycoses

Answer 7

Candida
Aspergillosis
ringworm

Question 8

Give an example each of the following classes of antifungals: triazoles, polyenes and echinocandins

Answer 8

Triazoles (fluconazole)

Polyenes (Amphotericin B)

Echinocandins (Caspofungin)

Question 9

Which antifungal drugs target the fungal cell wall?

Answer 9

Echinocandins