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Pharm > Antibiotic Class > Flashcards

Antibiotic Class Flashcards

1
Q

penicillins

A

amoxicillin

bacteriocidal - bacterial CW/membranes disrupters

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2
Q

carbapenems

A

meropenem

bacteriocidal - bacterial CW/membranes disrupters

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3
Q

monobactam

A

aztreonam

bacteriocidal - bacterial CW/membranes disrupters

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4
Q

glycopeptides (anti-staph agent)

A

vancomycin

bacteriocidal - bacterial CW/membranes disrupters

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5
Q

lipopeptides (anti-staph agent)

A

daptomycin

bacteriocidal - bacterial CW/membranes disrupters

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6
Q

anti-tb agents

bacteriocidal - bacterial CW/membranes disrupters

A

isoniazid, ethambutol

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7
Q

polymixins

A

polymixin B

bacteriocidal - bacterial CW/membranes disrupters

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8
Q

macrolides

A

azithromycin

bacterial protein synthesis inhibitors - bacteriostatic

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9
Q

tetracyclines

A

doxycycline

bacterial protein synthesis inhibitors - bacteriostatic

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10
Q

lincosamides

A

clindamycin

bacterial protein synthesis inhibitors - bacteriostatic

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11
Q

aminoglycosides

A

gentamicin

bacterial protein synthesis inhibitors - bacteriostatic

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12
Q

pleuromutilins

A

lefamulin

bacterial protein synthesis inhibitors - bacteriostatic

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13
Q

oxazolidinones (anti-staph agent)

A

linezolid

bacterial protein synthesis inhibitors - bacteriostatic

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14
Q

streptogramins (anti-staph agent)

A

quinupristan-dalfopristin

bacterial protein synthesis inhibitors - bacteriostatic

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15
Q

folate antagonists

A

trimethoprim-sulfamethoxazole

bacterial DNA/RNA function disruption - bacteriocidal

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16
Q

nitroimidazoles

A

metronidazole

bacterial DNA/RNA function disruption - bacteriocidal

17
Q

mupirocin

A

mupirocin

bacterial DNA/RNA function disruption - bacteriocidal

18
Q

nitrofurantoin

A

nitrofurantoin

bacterial DNA/RNA function disruption - bacteriocidal

19
Q

anti-tb agents

bacterial DNA/RNA function disruption - bacteriocidal

A

rifampin

20
Q

polyenes

A

nystatin, pores, unpleasant taste nausea diarrhea

21
Q

triazoles

A

itraconazole flucoconazole voriconazole posiconazole: block CYP450 enzyme in ergesterol synthesis, QT prolongation (headache nausea vomit cramp <10%), inhibit CYP3A4, CYP2C9, CYP2C19, avoid in 1st trimester

22
Q

imidazole

A

miconazole: headache, diarrhea <10%,
clotrimazole: nausea, LFT increases,
both pores, weak inhibitors CYP3A4, increase [serum] sulfonureas, warfarin

23
Q

echinocandins

A

-fungin

anidulafungin, caspofungin, micafungin

24
Q

pyrimidine analog

A

flucytosine: DNA/RNA fxn disrupt (chemo), avoid use in pregnancy

25
Q

triterpenoid

A

ibrexafungerp, avoid use in pregnancy

Pharm (2 decks)

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